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Main Authors: Chen, Lingyu, Zeng, Yawen, Wang, Yue, Wan, Peng, Ning, Guo-chen, Liao, Hongen, Zhang, Daoqiang, Chen, Fang
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2508.09886
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author Chen, Lingyu
Zeng, Yawen
Wang, Yue
Wan, Peng
Ning, Guo-chen
Liao, Hongen
Zhang, Daoqiang
Chen, Fang
author_facet Chen, Lingyu
Zeng, Yawen
Wang, Yue
Wan, Peng
Ning, Guo-chen
Liao, Hongen
Zhang, Daoqiang
Chen, Fang
contents Conventional single-dataset training often fails with new data distributions, especially in ultrasound (US) image analysis due to limited data, acoustic shadows, and speckle noise. Therefore, constructing a universal framework for multi-heterogeneous US datasets is imperative. However, a key challenge arises: how to effectively mitigate inter-dataset interference while preserving dataset-specific discriminative features for robust downstream task? Previous approaches utilize either a single source-specific decoder or a domain adaptation strategy, but these methods experienced a decline in performance when applied to other domains. Considering this, we propose a Universal Collaborative Mixture of Heterogeneous Source-Specific Experts (COME). Specifically, COME establishes dual structure-semantic shared experts that create a universal representation space and then collaborate with source-specific experts to extract discriminative features through providing complementary features. This design enables robust generalization by leveraging cross-datasets experience distributions and providing universal US priors for small-batch or unseen data scenarios. Extensive experiments under three evaluation modes (single-dataset, intra-organ, and inter-organ integration datasets) demonstrate COME's superiority, achieving significant mean AP improvements over state-of-the-art methods. Our project is available at: https://universalcome.github.io/UniversalCOME/.
format Preprint
id arxiv_https___arxiv_org_abs_2508_09886
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle COME: Dual Structure-Semantic Learning with Collaborative MoE for Universal Lesion Detection Across Heterogeneous Ultrasound Datasets
Chen, Lingyu
Zeng, Yawen
Wang, Yue
Wan, Peng
Ning, Guo-chen
Liao, Hongen
Zhang, Daoqiang
Chen, Fang
Computer Vision and Pattern Recognition
Artificial Intelligence
Computation and Language
Conventional single-dataset training often fails with new data distributions, especially in ultrasound (US) image analysis due to limited data, acoustic shadows, and speckle noise. Therefore, constructing a universal framework for multi-heterogeneous US datasets is imperative. However, a key challenge arises: how to effectively mitigate inter-dataset interference while preserving dataset-specific discriminative features for robust downstream task? Previous approaches utilize either a single source-specific decoder or a domain adaptation strategy, but these methods experienced a decline in performance when applied to other domains. Considering this, we propose a Universal Collaborative Mixture of Heterogeneous Source-Specific Experts (COME). Specifically, COME establishes dual structure-semantic shared experts that create a universal representation space and then collaborate with source-specific experts to extract discriminative features through providing complementary features. This design enables robust generalization by leveraging cross-datasets experience distributions and providing universal US priors for small-batch or unseen data scenarios. Extensive experiments under three evaluation modes (single-dataset, intra-organ, and inter-organ integration datasets) demonstrate COME's superiority, achieving significant mean AP improvements over state-of-the-art methods. Our project is available at: https://universalcome.github.io/UniversalCOME/.
title COME: Dual Structure-Semantic Learning with Collaborative MoE for Universal Lesion Detection Across Heterogeneous Ultrasound Datasets
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2508.09886