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Hauptverfasser: Gronsbell, Jessica, Thurston, Hilary, Dong, Lillian, Ferguson, Vanessa, Chaudhury, Diksha Sen, O'Neill, Braden, Sha, Katrina S., Bonneville, Rebecca
Format: Preprint
Veröffentlicht: 2025
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Online-Zugang:https://arxiv.org/abs/2508.14150
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author Gronsbell, Jessica
Thurston, Hilary
Dong, Lillian
Ferguson, Vanessa
Chaudhury, Diksha Sen
O'Neill, Braden
Sha, Katrina S.
Bonneville, Rebecca
author_facet Gronsbell, Jessica
Thurston, Hilary
Dong, Lillian
Ferguson, Vanessa
Chaudhury, Diksha Sen
O'Neill, Braden
Sha, Katrina S.
Bonneville, Rebecca
contents Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in their health record, such as diagnosis codes, medication histories, and information in clinical notes. Although intended to improve the visibility of trans and gender-expansive populations in EHR-based biomedical research, computational phenotyping raises significant methodological and ethical concerns related to the potential misuse of algorithm outputs. In this paper, we review current practices for computational phenotyping of gender and examine its challenges through a critical lens. We also highlight existing recommendations for biomedical researchers and propose priorities for future work in this domain.
format Preprint
id arxiv_https___arxiv_org_abs_2508_14150
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle When Algorithms Infer Gender: Revisiting Computational Phenotyping with Electronic Health Records Data
Gronsbell, Jessica
Thurston, Hilary
Dong, Lillian
Ferguson, Vanessa
Chaudhury, Diksha Sen
O'Neill, Braden
Sha, Katrina S.
Bonneville, Rebecca
Computers and Society
Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in their health record, such as diagnosis codes, medication histories, and information in clinical notes. Although intended to improve the visibility of trans and gender-expansive populations in EHR-based biomedical research, computational phenotyping raises significant methodological and ethical concerns related to the potential misuse of algorithm outputs. In this paper, we review current practices for computational phenotyping of gender and examine its challenges through a critical lens. We also highlight existing recommendations for biomedical researchers and propose priorities for future work in this domain.
title When Algorithms Infer Gender: Revisiting Computational Phenotyping with Electronic Health Records Data
topic Computers and Society
url https://arxiv.org/abs/2508.14150