Scalable FPGA Framework for Real-Time Denoising in High-Throughput Imaging: A DRAM-Optimized Pipeline using High-Level Synthesis

Fuente: arXiv
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Main Author: Liao, Weichien
Format: Preprint
Published: 2025
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author Liao, Weichien
author_facet Liao, Weichien
contents High-throughput imaging workflows, such as Parallel Rapid Imaging with Spectroscopic Mapping (PRISM), generate data at rates that exceed conventional real-time processing capabilities. We present a scalable FPGA-based preprocessing pipeline for real-time denoising, implemented via High-Level Synthesis (HLS) and optimized for DRAM-backed buffering. Our architecture performs frame subtraction and averaging directly on streamed image data, minimizing latency through burst-mode AXI4 interfaces. The resulting kernel operates below the inter-frame interval, enabling inline denoising and reducing dataset size for downstream CPU/GPU analysis. Validated under PRISM-scale acquisition, this modular FPGA framework offers a practical solution for latency-sensitive imaging workflows in spectroscopy and microscopy.
format Preprint
id arxiv_https___arxiv_org_abs_2508_14917
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Scalable FPGA Framework for Real-Time Denoising in High-Throughput Imaging: A DRAM-Optimized Pipeline using High-Level Synthesis
Liao, Weichien
Hardware Architecture
Computer Vision and Pattern Recognition
Distributed, Parallel, and Cluster Computing
Image and Video Processing
Signal Processing
Instrumentation and Detectors
High-throughput imaging workflows, such as Parallel Rapid Imaging with Spectroscopic Mapping (PRISM), generate data at rates that exceed conventional real-time processing capabilities. We present a scalable FPGA-based preprocessing pipeline for real-time denoising, implemented via High-Level Synthesis (HLS) and optimized for DRAM-backed buffering. Our architecture performs frame subtraction and averaging directly on streamed image data, minimizing latency through burst-mode AXI4 interfaces. The resulting kernel operates below the inter-frame interval, enabling inline denoising and reducing dataset size for downstream CPU/GPU analysis. Validated under PRISM-scale acquisition, this modular FPGA framework offers a practical solution for latency-sensitive imaging workflows in spectroscopy and microscopy.
title Scalable FPGA Framework for Real-Time Denoising in High-Throughput Imaging: A DRAM-Optimized Pipeline using High-Level Synthesis
topic Hardware Architecture
Computer Vision and Pattern Recognition
Distributed, Parallel, and Cluster Computing
Image and Video Processing
Signal Processing
Instrumentation and Detectors
url https://arxiv.org/abs/2508.14917