GraphMMP: A Graph Neural Network Model with Mutual Information and Global Fusion for Multimodal Medical Prognosis

Fuente: arXiv
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Main Authors: Shan, Xuhao, Ge, Ruiquan, Liu, Jikui, Wu, Linglong, Zhang, Chi, Liu, Siqi, Qin, Wenjian, Min, Wenwen, Elazab, Ahmed, Wang, Changmiao
Format: Preprint
Published: 2025
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_version_ 1866914002421940224
author Shan, Xuhao
Ge, Ruiquan
Liu, Jikui
Wu, Linglong
Zhang, Chi
Liu, Siqi
Qin, Wenjian
Min, Wenwen
Elazab, Ahmed
Wang, Changmiao
author_facet Shan, Xuhao
Ge, Ruiquan
Liu, Jikui
Wu, Linglong
Zhang, Chi
Liu, Siqi
Qin, Wenjian
Min, Wenwen
Elazab, Ahmed
Wang, Changmiao
contents In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions between heterogeneous data modalities with distinct characteristics while capturing both local and global dependencies across modalities. To address these challenges, this paper presents a two-stage multimodal prognosis model, GraphMMP, which is based on graph neural networks. The proposed model constructs feature graphs using mutual information and features a global fusion module built on Mamba, which significantly boosts prognosis performance. Empirical results show that GraphMMP surpasses existing methods on datasets related to liver prognosis and the METABRIC study, demonstrating its effectiveness in multimodal medical prognosis tasks.
format Preprint
id arxiv_https___arxiv_org_abs_2508_17478
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle GraphMMP: A Graph Neural Network Model with Mutual Information and Global Fusion for Multimodal Medical Prognosis
Shan, Xuhao
Ge, Ruiquan
Liu, Jikui
Wu, Linglong
Zhang, Chi
Liu, Siqi
Qin, Wenjian
Min, Wenwen
Elazab, Ahmed
Wang, Changmiao
Computer Vision and Pattern Recognition
In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions between heterogeneous data modalities with distinct characteristics while capturing both local and global dependencies across modalities. To address these challenges, this paper presents a two-stage multimodal prognosis model, GraphMMP, which is based on graph neural networks. The proposed model constructs feature graphs using mutual information and features a global fusion module built on Mamba, which significantly boosts prognosis performance. Empirical results show that GraphMMP surpasses existing methods on datasets related to liver prognosis and the METABRIC study, demonstrating its effectiveness in multimodal medical prognosis tasks.
title GraphMMP: A Graph Neural Network Model with Mutual Information and Global Fusion for Multimodal Medical Prognosis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2508.17478