Benchmarking Class Activation Map Methods for Explainable Brain Hemorrhage Classification on Hemorica Dataset

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Auteurs principaux: Rafati, Z., Hoseyni, M., Khoramdel, J., Nikoofard, A.
Format: Preprint
Publié: 2025
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author Rafati, Z.
Hoseyni, M.
Khoramdel, J.
Nikoofard, A.
author_facet Rafati, Z.
Hoseyni, M.
Khoramdel, J.
Nikoofard, A.
contents Explainable Artificial Intelligence (XAI) has become an essential component of medical imaging research, aiming to increase transparency and clinical trust in deep learning models. This study investigates brain hemorrhage diagnosis with a focus on explainability through Class Activation Mapping (CAM) techniques. A pipeline was developed to extract pixellevel segmentation and detection annotations from classification models using nine state-of-the-art CAM algorithms, applied across multiple network stages, and quantitatively evaluated on the Hemorica dataset, which uniquely provides both slice-level labels and high-quality segmentation masks. Metrics including Dice, IoU, and pixel-wise overlap were employed to benchmark CAM variants. Results show that the strongest localization performance occurred at stage 5 of EfficientNetV2S, with HiResCAM yielding the highest bounding-box alignment and AblationCAM achieving the best pixel-level Dice (0.57) and IoU (0.40), representing strong accuracy given that models were trained solely for classification without segmentation supervision. To the best of current knowledge, this is among the f irst works to quantitatively compare CAM methods for brain hemorrhage detection, establishing a reproducible benchmark and underscoring the potential of XAI-driven pipelines for clinically meaningful AI-assisted diagnosis.
format Preprint
id arxiv_https___arxiv_org_abs_2508_17699
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Benchmarking Class Activation Map Methods for Explainable Brain Hemorrhage Classification on Hemorica Dataset
Rafati, Z.
Hoseyni, M.
Khoramdel, J.
Nikoofard, A.
Computer Vision and Pattern Recognition
Quantitative Methods
Explainable Artificial Intelligence (XAI) has become an essential component of medical imaging research, aiming to increase transparency and clinical trust in deep learning models. This study investigates brain hemorrhage diagnosis with a focus on explainability through Class Activation Mapping (CAM) techniques. A pipeline was developed to extract pixellevel segmentation and detection annotations from classification models using nine state-of-the-art CAM algorithms, applied across multiple network stages, and quantitatively evaluated on the Hemorica dataset, which uniquely provides both slice-level labels and high-quality segmentation masks. Metrics including Dice, IoU, and pixel-wise overlap were employed to benchmark CAM variants. Results show that the strongest localization performance occurred at stage 5 of EfficientNetV2S, with HiResCAM yielding the highest bounding-box alignment and AblationCAM achieving the best pixel-level Dice (0.57) and IoU (0.40), representing strong accuracy given that models were trained solely for classification without segmentation supervision. To the best of current knowledge, this is among the f irst works to quantitatively compare CAM methods for brain hemorrhage detection, establishing a reproducible benchmark and underscoring the potential of XAI-driven pipelines for clinically meaningful AI-assisted diagnosis.
title Benchmarking Class Activation Map Methods for Explainable Brain Hemorrhage Classification on Hemorica Dataset
topic Computer Vision and Pattern Recognition
Quantitative Methods
url https://arxiv.org/abs/2508.17699