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Main Authors: Wang, Junda, Yao, Zonghai, Li, Lingxi, Qian, Junhui, Yang, Zhichao, Yu, Hong
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2508.20996
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author Wang, Junda
Yao, Zonghai
Li, Lingxi
Qian, Junhui
Yang, Zhichao
Yu, Hong
author_facet Wang, Junda
Yao, Zonghai
Li, Lingxi
Qian, Junhui
Yang, Zhichao
Yu, Hong
contents Substance use disorders (SUDs) affect millions of people, and relapses are common, requiring multi-session treatments. Access to care is limited, which contributes to the challenge of recovery support. We present \textbf{ChatThero}, an innovative low-cost, multi-session, stressor-aware, and memory-persistent autonomous \emph{language agent} designed to facilitate long-term behavior change and therapeutic support in addiction recovery. Unlike existing work that mostly finetuned large language models (LLMs) on patient-therapist conversation data, ChatThero was trained in a multi-agent simulated environment that mirrors real therapy. We created anonymized patient profiles from recovery communities (e.g., Reddit). We classify patients as \texttt{easy}, \texttt{medium}, and \texttt{difficult}, three scales representing their resistance to recovery. We created an external environment by introducing stressors (e.g., social determinants of health) to simulate real-world situations. We dynamically inject clinically-grounded therapeutic strategies (motivational interview and cognitive behavioral therapy). Our evaluation, conducted by both human (blinded clinicians) and LLM-as-Judge, shows that ChatThero is superior in empathy and clinical relevance. We show that stressor simulation improves robustness of ChatThero. Explicit stressors increase relapse-like setbacks, matching real-world patterns. We evaluate ChatThero with behavioral change metrics. On a 1--5 scale, ChatThero raises \texttt{motivation} by $+1.71$ points (from $2.39$ to $4.10$) and \texttt{confidence} by $+1.67$ points (from $1.52$ to $3.19$), substantially outperforming GPT-5. On \texttt{difficult} patients, ChatThero reaches the success milestone with $26\%$ fewer turns than GPT-5.
format Preprint
id arxiv_https___arxiv_org_abs_2508_20996
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle ChatThero: An LLM-Supported Chatbot for Behavior Change and Therapeutic Support in Addiction Recovery
Wang, Junda
Yao, Zonghai
Li, Lingxi
Qian, Junhui
Yang, Zhichao
Yu, Hong
Artificial Intelligence
Substance use disorders (SUDs) affect millions of people, and relapses are common, requiring multi-session treatments. Access to care is limited, which contributes to the challenge of recovery support. We present \textbf{ChatThero}, an innovative low-cost, multi-session, stressor-aware, and memory-persistent autonomous \emph{language agent} designed to facilitate long-term behavior change and therapeutic support in addiction recovery. Unlike existing work that mostly finetuned large language models (LLMs) on patient-therapist conversation data, ChatThero was trained in a multi-agent simulated environment that mirrors real therapy. We created anonymized patient profiles from recovery communities (e.g., Reddit). We classify patients as \texttt{easy}, \texttt{medium}, and \texttt{difficult}, three scales representing their resistance to recovery. We created an external environment by introducing stressors (e.g., social determinants of health) to simulate real-world situations. We dynamically inject clinically-grounded therapeutic strategies (motivational interview and cognitive behavioral therapy). Our evaluation, conducted by both human (blinded clinicians) and LLM-as-Judge, shows that ChatThero is superior in empathy and clinical relevance. We show that stressor simulation improves robustness of ChatThero. Explicit stressors increase relapse-like setbacks, matching real-world patterns. We evaluate ChatThero with behavioral change metrics. On a 1--5 scale, ChatThero raises \texttt{motivation} by $+1.71$ points (from $2.39$ to $4.10$) and \texttt{confidence} by $+1.67$ points (from $1.52$ to $3.19$), substantially outperforming GPT-5. On \texttt{difficult} patients, ChatThero reaches the success milestone with $26\%$ fewer turns than GPT-5.
title ChatThero: An LLM-Supported Chatbot for Behavior Change and Therapeutic Support in Addiction Recovery
topic Artificial Intelligence
url https://arxiv.org/abs/2508.20996