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Hauptverfasser: Perera, Dilruk, Habib, Gousia, Xu, Qianyi, Tan, Daniel J., He, Kai, Cambria, Erik, Feng, Mengling
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2508.21101
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author Perera, Dilruk
Habib, Gousia
Xu, Qianyi
Tan, Daniel J.
He, Kai
Cambria, Erik
Feng, Mengling
author_facet Perera, Dilruk
Habib, Gousia
Xu, Qianyi
Tan, Daniel J.
He, Kai
Cambria, Erik
Feng, Mengling
contents Reinforcement learning (RL) marks a fundamental shift in how artificial intelligence is applied in healthcare. Instead of merely predicting outcomes, RL actively decides interventions with long term goals. Unlike traditional models that operate on fixed associations, RL systems learn through trial, feedback, and long-term reward optimization, introducing transformative possibilities and new risks. From an information fusion lens, healthcare RL typically integrates multi-source signals such as vitals, labs clinical notes, imaging and device telemetry using temporal and decision-level mechanisms. These systems can operate within centralized, federated, or edge architectures to meet real-time clinical constraints, and naturally span data, features and decision fusion levels. This survey explore RL's rise in healthcare as more than a set of tools, rather a shift toward agentive intelligence in clinical environments. We first structure the landscape of RL techniques including model-based and model-free methods, offline and batch-constrained approaches, and emerging strategies for reward specification and uncertainty calibration through the lens of healthcare constraints. We then comprehensively analyze RL applications spanning critical care, chronic disease, mental health, diagnostics, and robotic assistance, identifying their trends, gaps, and translational bottlenecks. In contrast to prior reviews, we critically analyze RL's ethical, deployment, and reward design challenges, and synthesize lessons for safe, human-aligned policy learning. This paper serves as both a a technical roadmap and a critical reflection of RL's emerging transformative role in healthcare AI not as prediction machinery, but as agentive clinical intelligence.
format Preprint
id arxiv_https___arxiv_org_abs_2508_21101
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Beyond Prediction: Reinforcement Learning as the Defining Leap in Healthcare AI
Perera, Dilruk
Habib, Gousia
Xu, Qianyi
Tan, Daniel J.
He, Kai
Cambria, Erik
Feng, Mengling
Machine Learning
Artificial Intelligence
Reinforcement learning (RL) marks a fundamental shift in how artificial intelligence is applied in healthcare. Instead of merely predicting outcomes, RL actively decides interventions with long term goals. Unlike traditional models that operate on fixed associations, RL systems learn through trial, feedback, and long-term reward optimization, introducing transformative possibilities and new risks. From an information fusion lens, healthcare RL typically integrates multi-source signals such as vitals, labs clinical notes, imaging and device telemetry using temporal and decision-level mechanisms. These systems can operate within centralized, federated, or edge architectures to meet real-time clinical constraints, and naturally span data, features and decision fusion levels. This survey explore RL's rise in healthcare as more than a set of tools, rather a shift toward agentive intelligence in clinical environments. We first structure the landscape of RL techniques including model-based and model-free methods, offline and batch-constrained approaches, and emerging strategies for reward specification and uncertainty calibration through the lens of healthcare constraints. We then comprehensively analyze RL applications spanning critical care, chronic disease, mental health, diagnostics, and robotic assistance, identifying their trends, gaps, and translational bottlenecks. In contrast to prior reviews, we critically analyze RL's ethical, deployment, and reward design challenges, and synthesize lessons for safe, human-aligned policy learning. This paper serves as both a a technical roadmap and a critical reflection of RL's emerging transformative role in healthcare AI not as prediction machinery, but as agentive clinical intelligence.
title Beyond Prediction: Reinforcement Learning as the Defining Leap in Healthcare AI
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2508.21101