The Effect of Aqueous Medium on Nucleobase Shape Resonances: Insights from Microsolvation

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Hauptverfasser: Narayanan, Jishnu, Tripathi, Divya, Haritan, Idan, Dutta, Achintya Kumar
Format: Preprint
Veröffentlicht: 2025
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author Narayanan, Jishnu
Tripathi, Divya
Haritan, Idan
Dutta, Achintya Kumar
author_facet Narayanan, Jishnu
Tripathi, Divya
Haritan, Idan
Dutta, Achintya Kumar
contents We have studied the effect of microhydration on the shape resonances of uracil nucleobase. The resonance parameters were determined using the resonance via Padé approach along with the efficient wave function-based EA-EOM-DLPNO-CCSD method. Our results showed that the uracil resonances become stabilized with an increase in the extent of microsolvation. The energy of the resonances decreased, and the lifetime increased as the number of water molecules surrounding uracil was increased. It showed that ten water molecules are sufficient to make the lowest shape resonance of uracil a bound radical anionic state. Our results also indicate that the lowest energy resonance state may become a bound state under bulk solvation.
format Preprint
id arxiv_https___arxiv_org_abs_2509_00261
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle The Effect of Aqueous Medium on Nucleobase Shape Resonances: Insights from Microsolvation
Narayanan, Jishnu
Tripathi, Divya
Haritan, Idan
Dutta, Achintya Kumar
Chemical Physics
We have studied the effect of microhydration on the shape resonances of uracil nucleobase. The resonance parameters were determined using the resonance via Padé approach along with the efficient wave function-based EA-EOM-DLPNO-CCSD method. Our results showed that the uracil resonances become stabilized with an increase in the extent of microsolvation. The energy of the resonances decreased, and the lifetime increased as the number of water molecules surrounding uracil was increased. It showed that ten water molecules are sufficient to make the lowest shape resonance of uracil a bound radical anionic state. Our results also indicate that the lowest energy resonance state may become a bound state under bulk solvation.
title The Effect of Aqueous Medium on Nucleobase Shape Resonances: Insights from Microsolvation
topic Chemical Physics
url https://arxiv.org/abs/2509.00261