PoolPy: Automated combinatorial pooling for high-throughput molecular profiling
Fuente:
arXiv
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Preprint |
| Veröffentlicht: |
2025
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1866910032984014848 |
|---|---|
| author | Talamanca, Lorenzo Trouillon, Julian |
| author_facet | Talamanca, Lorenzo Trouillon, Julian |
| contents | Combinatorial group testing reduces screening costs and turnaround time but remains challenging to apply due to design complexity, varying applicability, and lack of implementation tools. Here we present PoolPy, a unified end-to-end framework and web platform to benchmark, automate and decode combinatorial group testing strategies tailored to application-specific constraints across assay modalities. We demonstrate PoolPy utility for protein-ligand interaction screening and genome-wide molecular profiling, enabling the scaling up of multi-readout functional assays. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2509_03481 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | PoolPy: Automated combinatorial pooling for high-throughput molecular profiling Talamanca, Lorenzo Trouillon, Julian Information Theory Combinatorial group testing reduces screening costs and turnaround time but remains challenging to apply due to design complexity, varying applicability, and lack of implementation tools. Here we present PoolPy, a unified end-to-end framework and web platform to benchmark, automate and decode combinatorial group testing strategies tailored to application-specific constraints across assay modalities. We demonstrate PoolPy utility for protein-ligand interaction screening and genome-wide molecular profiling, enabling the scaling up of multi-readout functional assays. |
| title | PoolPy: Automated combinatorial pooling for high-throughput molecular profiling |
| topic | Information Theory |
| url | https://arxiv.org/abs/2509.03481 |