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Hauptverfasser: Li, Tingyou, Xu, Zixin, Gao, Zirui, Yan, Hanfei, Huang, Xiaojing, Li, Jizhou
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2509.04402
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author Li, Tingyou
Xu, Zixin
Gao, Zirui
Yan, Hanfei
Huang, Xiaojing
Li, Jizhou
author_facet Li, Tingyou
Xu, Zixin
Gao, Zirui
Yan, Hanfei
Huang, Xiaojing
Li, Jizhou
contents X-ray ptychography provides exceptional nanoscale resolution and is widely applied in materials science, biology, and nanotechnology. However, its full potential is constrained by the critical challenge of accurately reconstructing images when the illuminating probe is unknown. Conventional iterative methods and deep learning approaches are often suboptimal, particularly under the low-signal conditions inherent to low-dose and high-speed experiments. These limitations compromise reconstruction fidelity and restrict the broader adoption of the technique. In this work, we introduce the Ptychographic Implicit Neural Representation (PtyINR), a self-supervised framework that simultaneously addresses the object and probe recovery problem. By parameterizing both as continuous neural representations, PtyINR performs end-to-end reconstruction directly from raw diffraction patterns without requiring any pre-characterization of the probe. Extensive evaluations demonstrate that PtyINR achieves superior reconstruction quality on both simulated and experimental data, with remarkable robustness under challenging low-signal conditions. Furthermore, PtyINR offers a generalizable, physics-informed framework for addressing probe-dependent inverse problems, making it applicable to a wide range of computational microscopy problems.
format Preprint
id arxiv_https___arxiv_org_abs_2509_04402
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Learning neural representations for X-ray ptychography reconstruction with unknown probes
Li, Tingyou
Xu, Zixin
Gao, Zirui
Yan, Hanfei
Huang, Xiaojing
Li, Jizhou
Computer Vision and Pattern Recognition
X-ray ptychography provides exceptional nanoscale resolution and is widely applied in materials science, biology, and nanotechnology. However, its full potential is constrained by the critical challenge of accurately reconstructing images when the illuminating probe is unknown. Conventional iterative methods and deep learning approaches are often suboptimal, particularly under the low-signal conditions inherent to low-dose and high-speed experiments. These limitations compromise reconstruction fidelity and restrict the broader adoption of the technique. In this work, we introduce the Ptychographic Implicit Neural Representation (PtyINR), a self-supervised framework that simultaneously addresses the object and probe recovery problem. By parameterizing both as continuous neural representations, PtyINR performs end-to-end reconstruction directly from raw diffraction patterns without requiring any pre-characterization of the probe. Extensive evaluations demonstrate that PtyINR achieves superior reconstruction quality on both simulated and experimental data, with remarkable robustness under challenging low-signal conditions. Furthermore, PtyINR offers a generalizable, physics-informed framework for addressing probe-dependent inverse problems, making it applicable to a wide range of computational microscopy problems.
title Learning neural representations for X-ray ptychography reconstruction with unknown probes
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2509.04402