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| Main Authors: | , |
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| Format: | Preprint |
| Published: |
2025
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2509.05464 |
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Table of Contents:
- Ultrafast power Doppler imaging (uPDI) has become a powerful tool for both research and clinical applications. However, existing simulation tools are insufficient for generating quantitatively accurate three-dimensional (3D) flow fields with tissue motion mimicking in vivo conditions. In this study, we present an open-source framework, named 3D-Fully Quantitative Flow (3D-FQFlow), to provide quantitative modeling of 3D vascular hemodynamics with physiologically realistic tissue motion for uPDI. The framework can perform quantitative modeling of both hemodynamics and tissue motion for either user-defined or clinical-derived vasculatures. Besides, it also integrates a GPU-accelerated image processing and reconstruction module. We demonstrate the performance of 3D-FQFlow using both synthetic vascular structures and clinical datasets. This framework could provide essential ground-truth simulation models to support the development, validation, and benchmarking of uPDI techniques. The source code is freely available online athttps://github.com/FortuneOU/3D-FQFlow.