SAM$^{*}$: Task-Adaptive SAM with Physics-Guided Rewards

Fuente: arXiv
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Hauptverfasser: Barakati, Kamyar, Pratiush, Utkarsh, Sanchez, Sheryl L., Raghavan, Aditya, Milliron, Delia J., Ahmadi, Mahshid, Rack, Philip D., Kalinin, Sergei V.
Format: Preprint
Veröffentlicht: 2025
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author Barakati, Kamyar
Pratiush, Utkarsh
Sanchez, Sheryl L.
Raghavan, Aditya
Milliron, Delia J.
Ahmadi, Mahshid
Rack, Philip D.
Kalinin, Sergei V.
author_facet Barakati, Kamyar
Pratiush, Utkarsh
Sanchez, Sheryl L.
Raghavan, Aditya
Milliron, Delia J.
Ahmadi, Mahshid
Rack, Philip D.
Kalinin, Sergei V.
contents Image segmentation is a critical task in microscopy, essential for accurately analyzing and interpreting complex visual data. This task can be performed using custom models trained on domain-specific datasets, transfer learning from pre-trained models, or foundational models that offer broad applicability. However, foundational models often present a considerable number of non-transparent tuning parameters that require extensive manual optimization, limiting their usability for real-time streaming data analysis. Here, we introduce a reward function-based optimization to fine-tune foundational models and illustrate this approach for SAM (Segment Anything Model) framework by Meta. The reward functions can be constructed to represent the physics of the imaged system, including particle size distributions, geometries, and other criteria. By integrating a reward-driven optimization framework, we enhance SAM's adaptability and performance, leading to an optimized variant, SAM$^{*}$, that better aligns with the requirements of diverse segmentation tasks and particularly allows for real-time streaming data segmentation. We demonstrate the effectiveness of this approach in microscopy imaging, where precise segmentation is crucial for analyzing cellular structures, material interfaces, and nanoscale features.
format Preprint
id arxiv_https___arxiv_org_abs_2509_07047
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SAM$^{*}$: Task-Adaptive SAM with Physics-Guided Rewards
Barakati, Kamyar
Pratiush, Utkarsh
Sanchez, Sheryl L.
Raghavan, Aditya
Milliron, Delia J.
Ahmadi, Mahshid
Rack, Philip D.
Kalinin, Sergei V.
Computer Vision and Pattern Recognition
Materials Science
Machine Learning
Image segmentation is a critical task in microscopy, essential for accurately analyzing and interpreting complex visual data. This task can be performed using custom models trained on domain-specific datasets, transfer learning from pre-trained models, or foundational models that offer broad applicability. However, foundational models often present a considerable number of non-transparent tuning parameters that require extensive manual optimization, limiting their usability for real-time streaming data analysis. Here, we introduce a reward function-based optimization to fine-tune foundational models and illustrate this approach for SAM (Segment Anything Model) framework by Meta. The reward functions can be constructed to represent the physics of the imaged system, including particle size distributions, geometries, and other criteria. By integrating a reward-driven optimization framework, we enhance SAM's adaptability and performance, leading to an optimized variant, SAM$^{*}$, that better aligns with the requirements of diverse segmentation tasks and particularly allows for real-time streaming data segmentation. We demonstrate the effectiveness of this approach in microscopy imaging, where precise segmentation is crucial for analyzing cellular structures, material interfaces, and nanoscale features.
title SAM$^{*}$: Task-Adaptive SAM with Physics-Guided Rewards
topic Computer Vision and Pattern Recognition
Materials Science
Machine Learning
url https://arxiv.org/abs/2509.07047