A mathematical model of vaccine hesitancy: Analysing the impact of political trends and the interaction across age and education groups in the USA

Fuente: arXiv
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Auteurs principaux: Ali, Wajid, Mohamadichamgavi, Javad, Ramirez, Juan, Aguilar, Jose, Anta, Antonio Fernández, Sharkey, Kieran J.
Format: Preprint
Publié: 2025
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author Ali, Wajid
Mohamadichamgavi, Javad
Ramirez, Juan
Aguilar, Jose
Anta, Antonio Fernández
Sharkey, Kieran J.
author_facet Ali, Wajid
Mohamadichamgavi, Javad
Ramirez, Juan
Aguilar, Jose
Anta, Antonio Fernández
Sharkey, Kieran J.
contents Vaccination against the SARS-CoV-2 disease has significantly reduced its mortality rate and spread. However, despite its availability, a considerable proportion of the public has either refused or delayed getting vaccinated. This reluctance is known as vaccine hesitancy. The aim of this paper is to present a mathematical model to investigate how social interaction can impact vaccine hesitancy. The model describes the temporal transitions between different vaccination classes of the population (those vaccinated, those who are not yet vaccinated but agree to be vaccinated, and those who refuse). We apply the model to state and national survey data from the USA to estimate model parameters that quantify the rates at which public opinion on vaccination changes. Moreover, we investigate how political trends and demographic factors, such as age and education, impact these parameters. Our results show that state-level political affiliation, age, and educational level shape opinions on vaccination and have a strong influence on the temporal dynamics of attitude changes.
format Preprint
id arxiv_https___arxiv_org_abs_2509_07712
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A mathematical model of vaccine hesitancy: Analysing the impact of political trends and the interaction across age and education groups in the USA
Ali, Wajid
Mohamadichamgavi, Javad
Ramirez, Juan
Aguilar, Jose
Anta, Antonio Fernández
Sharkey, Kieran J.
Populations and Evolution
Vaccination against the SARS-CoV-2 disease has significantly reduced its mortality rate and spread. However, despite its availability, a considerable proportion of the public has either refused or delayed getting vaccinated. This reluctance is known as vaccine hesitancy. The aim of this paper is to present a mathematical model to investigate how social interaction can impact vaccine hesitancy. The model describes the temporal transitions between different vaccination classes of the population (those vaccinated, those who are not yet vaccinated but agree to be vaccinated, and those who refuse). We apply the model to state and national survey data from the USA to estimate model parameters that quantify the rates at which public opinion on vaccination changes. Moreover, we investigate how political trends and demographic factors, such as age and education, impact these parameters. Our results show that state-level political affiliation, age, and educational level shape opinions on vaccination and have a strong influence on the temporal dynamics of attitude changes.
title A mathematical model of vaccine hesitancy: Analysing the impact of political trends and the interaction across age and education groups in the USA
topic Populations and Evolution
url https://arxiv.org/abs/2509.07712