LAVA: Language Model Assisted Verbal Autopsy for Cause-of-Death Determination

Fuente: arXiv
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Autores principales: Chen, Yiqun T., McCormick, Tyler H., Liu, Li, Datta, Abhirup
Formato: Preprint
Publicado: 2025
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author Chen, Yiqun T.
McCormick, Tyler H.
Liu, Li
Datta, Abhirup
author_facet Chen, Yiqun T.
McCormick, Tyler H.
Liu, Li
Datta, Abhirup
contents Verbal autopsy (VA) is a critical tool for estimating causes of death in resource-limited settings where medical certification is unavailable. This study presents LA-VA, a proof-of-concept pipeline that combines Large Language Models (LLMs) with traditional algorithmic approaches and embedding-based classification for improved cause-of-death prediction. Using the Population Health Metrics Research Consortium (PHMRC) dataset across three age categories (Adult: 7,580; Child: 1,960; Neonate: 2,438), we evaluate multiple approaches: GPT-5 predictions, LCVA baseline, text embeddings, and meta-learner ensembles. Our results demonstrate that GPT-5 achieves the highest individual performance with average test site accuracies of 48.6% (Adult), 50.5% (Child), and 53.5% (Neonate), outperforming traditional statistical machine learning baselines by 5-10%. Our findings suggest that simple off-the-shelf LLM-assisted approaches could substantially improve verbal autopsy accuracy, with important implications for global health surveillance in low-resource settings.
format Preprint
id arxiv_https___arxiv_org_abs_2509_09602
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle LAVA: Language Model Assisted Verbal Autopsy for Cause-of-Death Determination
Chen, Yiqun T.
McCormick, Tyler H.
Liu, Li
Datta, Abhirup
Computation and Language
Applications
Verbal autopsy (VA) is a critical tool for estimating causes of death in resource-limited settings where medical certification is unavailable. This study presents LA-VA, a proof-of-concept pipeline that combines Large Language Models (LLMs) with traditional algorithmic approaches and embedding-based classification for improved cause-of-death prediction. Using the Population Health Metrics Research Consortium (PHMRC) dataset across three age categories (Adult: 7,580; Child: 1,960; Neonate: 2,438), we evaluate multiple approaches: GPT-5 predictions, LCVA baseline, text embeddings, and meta-learner ensembles. Our results demonstrate that GPT-5 achieves the highest individual performance with average test site accuracies of 48.6% (Adult), 50.5% (Child), and 53.5% (Neonate), outperforming traditional statistical machine learning baselines by 5-10%. Our findings suggest that simple off-the-shelf LLM-assisted approaches could substantially improve verbal autopsy accuracy, with important implications for global health surveillance in low-resource settings.
title LAVA: Language Model Assisted Verbal Autopsy for Cause-of-Death Determination
topic Computation and Language
Applications
url https://arxiv.org/abs/2509.09602