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Main Authors: Fürböck, Christoph, Weiser, Paul, Mitic, Branko, Seeböck, Philipp, Helbich, Thomas, Langs, Georg
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2509.11406
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author Fürböck, Christoph
Weiser, Paul
Mitic, Branko
Seeböck, Philipp
Helbich, Thomas
Langs, Georg
author_facet Fürböck, Christoph
Weiser, Paul
Mitic, Branko
Seeböck, Philipp
Helbich, Thomas
Langs, Georg
contents In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or repurpose dropout learning schemes, limiting robustness and generalizability. To address this, we propose a hypernetwork-based method that dynamically generates task-specific classification models conditioned on the set of available modalities. Instead of training a fixed model, a hypernetwork learns to predict the parameters of a task model adapted to available modalities, enabling training and inference on all samples, regardless of completeness. We compare this approach with (1) models trained only on complete data, (2) state of the art channel dropout methods, and (3) an imputation-based method, using artificially incomplete datasets to systematically analyze robustness to missing modalities. Results demonstrate superior adaptability of our method, outperforming state of the art approaches with an absolute increase in accuracy of up to 8% when trained on a dataset with 25% completeness (75% of training data with missing modalities). By enabling a single model to generalize across all modality configurations, our approach provides an efficient solution for real-world multi-modal medical data analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2509_11406
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle No Modality Left Behind: Dynamic Model Generation for Incomplete Medical Data
Fürböck, Christoph
Weiser, Paul
Mitic, Branko
Seeböck, Philipp
Helbich, Thomas
Langs, Georg
Computer Vision and Pattern Recognition
In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or repurpose dropout learning schemes, limiting robustness and generalizability. To address this, we propose a hypernetwork-based method that dynamically generates task-specific classification models conditioned on the set of available modalities. Instead of training a fixed model, a hypernetwork learns to predict the parameters of a task model adapted to available modalities, enabling training and inference on all samples, regardless of completeness. We compare this approach with (1) models trained only on complete data, (2) state of the art channel dropout methods, and (3) an imputation-based method, using artificially incomplete datasets to systematically analyze robustness to missing modalities. Results demonstrate superior adaptability of our method, outperforming state of the art approaches with an absolute increase in accuracy of up to 8% when trained on a dataset with 25% completeness (75% of training data with missing modalities). By enabling a single model to generalize across all modality configurations, our approach provides an efficient solution for real-world multi-modal medical data analysis.
title No Modality Left Behind: Dynamic Model Generation for Incomplete Medical Data
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2509.11406