NeuroStrike: Neuron-Level Attacks on Aligned LLMs

Fuente: arXiv
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Main Authors: Wu, Lichao, Behrouzi, Sasha, Rostami, Mohamadreza, Thang, Maximilian, Picek, Stjepan, Sadeghi, Ahmad-Reza
Format: Preprint
Published: 2025
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author Wu, Lichao
Behrouzi, Sasha
Rostami, Mohamadreza
Thang, Maximilian
Picek, Stjepan
Sadeghi, Ahmad-Reza
author_facet Wu, Lichao
Behrouzi, Sasha
Rostami, Mohamadreza
Thang, Maximilian
Picek, Stjepan
Sadeghi, Ahmad-Reza
contents Safety alignment is critical for the ethical deployment of large language models (LLMs), guiding them to avoid generating harmful or unethical content. Current alignment techniques, such as supervised fine-tuning and reinforcement learning from human feedback, remain fragile and can be bypassed by carefully crafted adversarial prompts. Unfortunately, such attacks rely on trial and error, lack generalizability across models, and are constrained by scalability and reliability. This paper presents NeuroStrike, a novel and generalizable attack framework that exploits a fundamental vulnerability introduced by alignment techniques: the reliance on sparse, specialized safety neurons responsible for detecting and suppressing harmful inputs. We apply NeuroStrike to both white-box and black-box settings: In the white-box setting, NeuroStrike identifies safety neurons through feedforward activation analysis and prunes them during inference to disable safety mechanisms. In the black-box setting, we propose the first LLM profiling attack, which leverages safety neuron transferability by training adversarial prompt generators on open-weight surrogate models and then deploying them against black-box and proprietary targets. We evaluate NeuroStrike on over 20 open-weight LLMs from major LLM developers. By removing less than 0.6% of neurons in targeted layers, NeuroStrike achieves an average attack success rate (ASR) of 76.9% using only vanilla malicious prompts. Moreover, Neurostrike generalizes to four multimodal LLMs with 100% ASR on unsafe image inputs. Safety neurons transfer effectively across architectures, raising ASR to 78.5% on 11 fine-tuned models and 77.7% on five distilled models. The black-box LLM profiling attack achieves an average ASR of 63.7% across five black-box models, including the Google Gemini family.
format Preprint
id arxiv_https___arxiv_org_abs_2509_11864
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle NeuroStrike: Neuron-Level Attacks on Aligned LLMs
Wu, Lichao
Behrouzi, Sasha
Rostami, Mohamadreza
Thang, Maximilian
Picek, Stjepan
Sadeghi, Ahmad-Reza
Cryptography and Security
Safety alignment is critical for the ethical deployment of large language models (LLMs), guiding them to avoid generating harmful or unethical content. Current alignment techniques, such as supervised fine-tuning and reinforcement learning from human feedback, remain fragile and can be bypassed by carefully crafted adversarial prompts. Unfortunately, such attacks rely on trial and error, lack generalizability across models, and are constrained by scalability and reliability. This paper presents NeuroStrike, a novel and generalizable attack framework that exploits a fundamental vulnerability introduced by alignment techniques: the reliance on sparse, specialized safety neurons responsible for detecting and suppressing harmful inputs. We apply NeuroStrike to both white-box and black-box settings: In the white-box setting, NeuroStrike identifies safety neurons through feedforward activation analysis and prunes them during inference to disable safety mechanisms. In the black-box setting, we propose the first LLM profiling attack, which leverages safety neuron transferability by training adversarial prompt generators on open-weight surrogate models and then deploying them against black-box and proprietary targets. We evaluate NeuroStrike on over 20 open-weight LLMs from major LLM developers. By removing less than 0.6% of neurons in targeted layers, NeuroStrike achieves an average attack success rate (ASR) of 76.9% using only vanilla malicious prompts. Moreover, Neurostrike generalizes to four multimodal LLMs with 100% ASR on unsafe image inputs. Safety neurons transfer effectively across architectures, raising ASR to 78.5% on 11 fine-tuned models and 77.7% on five distilled models. The black-box LLM profiling attack achieves an average ASR of 63.7% across five black-box models, including the Google Gemini family.
title NeuroStrike: Neuron-Level Attacks on Aligned LLMs
topic Cryptography and Security
url https://arxiv.org/abs/2509.11864