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Bibliographic Details
Main Authors: He, Nathan, Chen, Cody
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2509.12287
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author He, Nathan
Chen, Cody
author_facet He, Nathan
Chen, Cody
contents Existing deep learning models for chest radiology often neglect patient metadata, limiting diagnostic accuracy and fairness. To bridge this gap, we introduce MetaCheX, a novel multimodal framework that integrates chest X-ray images with structured patient metadata to replicate clinical decision-making. Our approach combines a convolutional neural network (CNN) backbone with metadata processed by a multilayer perceptron through a shared classifier. Evaluated on the CheXpert Plus dataset, MetaCheX consistently outperformed radiograph-only baseline models across multiple CNN architectures. By integrating metadata, the overall diagnostic accuracy was significantly improved, measured by an increase in AUROC. The results of this study demonstrate that metadata reduces algorithmic bias and enhances model generalizability across diverse patient populations. MetaCheX advances clinical artificial intelligence toward robust, context-aware radiographic disease detection.
format Preprint
id arxiv_https___arxiv_org_abs_2509_12287
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Radiographic Disease Detection with MetaCheX, a Context-Aware Multimodal Model
He, Nathan
Chen, Cody
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Existing deep learning models for chest radiology often neglect patient metadata, limiting diagnostic accuracy and fairness. To bridge this gap, we introduce MetaCheX, a novel multimodal framework that integrates chest X-ray images with structured patient metadata to replicate clinical decision-making. Our approach combines a convolutional neural network (CNN) backbone with metadata processed by a multilayer perceptron through a shared classifier. Evaluated on the CheXpert Plus dataset, MetaCheX consistently outperformed radiograph-only baseline models across multiple CNN architectures. By integrating metadata, the overall diagnostic accuracy was significantly improved, measured by an increase in AUROC. The results of this study demonstrate that metadata reduces algorithmic bias and enhances model generalizability across diverse patient populations. MetaCheX advances clinical artificial intelligence toward robust, context-aware radiographic disease detection.
title Enhancing Radiographic Disease Detection with MetaCheX, a Context-Aware Multimodal Model
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2509.12287