Differentially private federated learning for localized control of infectious disease dynamics

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Main Authors: Kerkouche, Raouf, Zunker, Henrik, Fritz, Mario, Kühn, Martin J.
Format: Preprint
Published: 2025
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author Kerkouche, Raouf
Zunker, Henrik
Fritz, Mario
Kühn, Martin J.
author_facet Kerkouche, Raouf
Zunker, Henrik
Fritz, Mario
Kühn, Martin J.
contents In times of epidemics, swift reaction is necessary to mitigate epidemic spreading. For this reaction, localized approaches have several advantages, limiting necessary resources and reducing the impact of interventions on a larger scale. However, training a separate machine learning (ML) model on a local scale is often not feasible due to limited available data. Centralizing the data is also challenging because of its high sensitivity and privacy constraints. In this study, we consider a localized strategy based on the German counties and communities managed by the related local health authorities (LHA). For the preservation of privacy to not oppose the availability of detailed situational data, we propose a privacy-preserving forecasting method that can assist public health experts and decision makers. ML methods with federated learning (FL) train a shared model without centralizing raw data. Considering the counties, communities or LHAs as clients and finding a balance between utility and privacy, we study a FL framework with client-level differential privacy (DP). We train a shared multilayer perceptron on sliding windows of recent case counts to forecast the number of cases, while clients exchange only norm-clipped updates and the server aggregated updates with DP noise. We evaluate the approach on COVID-19 data on county-level during two phases. As expected, very strict privacy yields unstable, unusable forecasts. At a moderately strong level, the DP model closely approaches the non-DP model: R2 around 0.94 (vs. 0.95) and mean absolute percentage error (MAPE) of 26 % in November 2020; R2 around 0.88 (vs. 0.93) and MAPE of 21 % in March 2022. Overall, client-level DP-FL can deliver useful county-level predictions with strong privacy guarantees, and viable privacy budgets depend on epidemic phase, allowing privacy-compliant collaboration among health authorities for local forecasting.
format Preprint
id arxiv_https___arxiv_org_abs_2509_14024
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Differentially private federated learning for localized control of infectious disease dynamics
Kerkouche, Raouf
Zunker, Henrik
Fritz, Mario
Kühn, Martin J.
Machine Learning
68T07, 68P27, 92-08, 92-10
In times of epidemics, swift reaction is necessary to mitigate epidemic spreading. For this reaction, localized approaches have several advantages, limiting necessary resources and reducing the impact of interventions on a larger scale. However, training a separate machine learning (ML) model on a local scale is often not feasible due to limited available data. Centralizing the data is also challenging because of its high sensitivity and privacy constraints. In this study, we consider a localized strategy based on the German counties and communities managed by the related local health authorities (LHA). For the preservation of privacy to not oppose the availability of detailed situational data, we propose a privacy-preserving forecasting method that can assist public health experts and decision makers. ML methods with federated learning (FL) train a shared model without centralizing raw data. Considering the counties, communities or LHAs as clients and finding a balance between utility and privacy, we study a FL framework with client-level differential privacy (DP). We train a shared multilayer perceptron on sliding windows of recent case counts to forecast the number of cases, while clients exchange only norm-clipped updates and the server aggregated updates with DP noise. We evaluate the approach on COVID-19 data on county-level during two phases. As expected, very strict privacy yields unstable, unusable forecasts. At a moderately strong level, the DP model closely approaches the non-DP model: R2 around 0.94 (vs. 0.95) and mean absolute percentage error (MAPE) of 26 % in November 2020; R2 around 0.88 (vs. 0.93) and MAPE of 21 % in March 2022. Overall, client-level DP-FL can deliver useful county-level predictions with strong privacy guarantees, and viable privacy budgets depend on epidemic phase, allowing privacy-compliant collaboration among health authorities for local forecasting.
title Differentially private federated learning for localized control of infectious disease dynamics
topic Machine Learning
68T07, 68P27, 92-08, 92-10
url https://arxiv.org/abs/2509.14024