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Main Authors: Xiaodong, Kuang, Bingxuan, Li, Yuan, Li, Fan, Rao, Gege, Ma, Qingguo, Xie, P, Mok Greta S, Huafeng, Liu, Wentao, Zhu
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2509.18801
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author Xiaodong, Kuang
Bingxuan, Li
Yuan, Li
Fan, Rao
Gege, Ma
Qingguo, Xie
P, Mok Greta S
Huafeng, Liu
Wentao, Zhu
author_facet Xiaodong, Kuang
Bingxuan, Li
Yuan, Li
Fan, Rao
Gege, Ma
Qingguo, Xie
P, Mok Greta S
Huafeng, Liu
Wentao, Zhu
contents Achieving high image quality for temporal frames in dynamic positron emission tomography (PET) is challenging due to the limited statistic especially for the short frames. Recent studies have shown that deep learning (DL) is useful in a wide range of medical image denoising tasks. In this paper, we propose a model-based neural network for dynamic PET image denoising. The inter-frame spatial correlation and intra-frame structural consistency in dynamic PET are used to establish the kernel space-based multidimensional sparse (KMDS) model. We then substitute the inherent forms of the parameter estimation with neural networks to enable adaptive parameters optimization, forming the end-to-end neural KMDS-Net. Extensive experimental results from simulated and real data demonstrate that the neural KMDS-Net exhibits strong denoising performance for dynamic PET, outperforming previous baseline methods. The proposed method may be used to effectively achieve high temporal and spatial resolution for dynamic PET. Our source code is available at https://github.com/Kuangxd/Neural-KMDS-Net/tree/main.
format Preprint
id arxiv_https___arxiv_org_abs_2509_18801
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Kernel Space-based Multidimensional Sparse Model for Dynamic PET Image Denoising
Xiaodong, Kuang
Bingxuan, Li
Yuan, Li
Fan, Rao
Gege, Ma
Qingguo, Xie
P, Mok Greta S
Huafeng, Liu
Wentao, Zhu
Computer Vision and Pattern Recognition
Artificial Intelligence
Achieving high image quality for temporal frames in dynamic positron emission tomography (PET) is challenging due to the limited statistic especially for the short frames. Recent studies have shown that deep learning (DL) is useful in a wide range of medical image denoising tasks. In this paper, we propose a model-based neural network for dynamic PET image denoising. The inter-frame spatial correlation and intra-frame structural consistency in dynamic PET are used to establish the kernel space-based multidimensional sparse (KMDS) model. We then substitute the inherent forms of the parameter estimation with neural networks to enable adaptive parameters optimization, forming the end-to-end neural KMDS-Net. Extensive experimental results from simulated and real data demonstrate that the neural KMDS-Net exhibits strong denoising performance for dynamic PET, outperforming previous baseline methods. The proposed method may be used to effectively achieve high temporal and spatial resolution for dynamic PET. Our source code is available at https://github.com/Kuangxd/Neural-KMDS-Net/tree/main.
title A Kernel Space-based Multidimensional Sparse Model for Dynamic PET Image Denoising
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2509.18801