A co-evolving agentic AI system for medical imaging analysis

Fuente: arXiv
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Main Authors: Li, Songhao, Xu, Jonathan, Bao, Tiancheng, Liu, Yuxuan, Liu, Yuchen, Liu, Yihang, Wang, Lilin, Lei, Wenhui, Wang, Sheng, Xu, Yinuo, Cui, Yan, Yao, Jialu, Koga, Shunsuke, Huang, Zhi
Format: Preprint
Published: 2025
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author Li, Songhao
Xu, Jonathan
Bao, Tiancheng
Liu, Yuxuan
Liu, Yuchen
Liu, Yihang
Wang, Lilin
Lei, Wenhui
Wang, Sheng
Xu, Yinuo
Cui, Yan
Yao, Jialu
Koga, Shunsuke
Huang, Zhi
author_facet Li, Songhao
Xu, Jonathan
Bao, Tiancheng
Liu, Yuxuan
Liu, Yuchen
Liu, Yihang
Wang, Lilin
Lei, Wenhui
Wang, Sheng
Xu, Yinuo
Cui, Yan
Yao, Jialu
Koga, Shunsuke
Huang, Zhi
contents Agentic AI is rapidly advancing in healthcare and biomedical research. However, in medical image analysis, their performance and adoption remain limited due to the lack of a robust ecosystem, insufficient toolsets, and the absence of real-time interactive expert feedback. Here we present "TissueLab", a co-evolving agentic AI system that allows researchers to ask direct questions, automatically plan and generate explainable workflows, and conduct real-time analyses where experts can visualize intermediate results and refine them. TissueLab integrates tool factories across pathology, radiology, and spatial omics domains. By standardizing inputs, outputs, and capabilities of diverse tools, the system determines when and how to invoke them to address research and clinical questions. Across diverse tasks with clinically meaningful quantifications that inform staging, prognosis, and treatment planning, TissueLab achieves state-of-the-art performance compared with end-to-end vision-language models (VLMs) and other agentic AI systems such as GPT-5. Moreover, TissueLab continuously learns from clinicians, evolving toward improved classifiers and more effective decision strategies. With active learning, it delivers accurate results in unseen disease contexts within minutes, without requiring massive datasets or prolonged retraining. Released as a sustainable open-source ecosystem, TissueLab aims to accelerate computational research and translational adoption in medical imaging while establishing a foundation for the next generation of medical AI.
format Preprint
id arxiv_https___arxiv_org_abs_2509_20279
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A co-evolving agentic AI system for medical imaging analysis
Li, Songhao
Xu, Jonathan
Bao, Tiancheng
Liu, Yuxuan
Liu, Yuchen
Liu, Yihang
Wang, Lilin
Lei, Wenhui
Wang, Sheng
Xu, Yinuo
Cui, Yan
Yao, Jialu
Koga, Shunsuke
Huang, Zhi
Computer Vision and Pattern Recognition
Quantitative Methods
Agentic AI is rapidly advancing in healthcare and biomedical research. However, in medical image analysis, their performance and adoption remain limited due to the lack of a robust ecosystem, insufficient toolsets, and the absence of real-time interactive expert feedback. Here we present "TissueLab", a co-evolving agentic AI system that allows researchers to ask direct questions, automatically plan and generate explainable workflows, and conduct real-time analyses where experts can visualize intermediate results and refine them. TissueLab integrates tool factories across pathology, radiology, and spatial omics domains. By standardizing inputs, outputs, and capabilities of diverse tools, the system determines when and how to invoke them to address research and clinical questions. Across diverse tasks with clinically meaningful quantifications that inform staging, prognosis, and treatment planning, TissueLab achieves state-of-the-art performance compared with end-to-end vision-language models (VLMs) and other agentic AI systems such as GPT-5. Moreover, TissueLab continuously learns from clinicians, evolving toward improved classifiers and more effective decision strategies. With active learning, it delivers accurate results in unseen disease contexts within minutes, without requiring massive datasets or prolonged retraining. Released as a sustainable open-source ecosystem, TissueLab aims to accelerate computational research and translational adoption in medical imaging while establishing a foundation for the next generation of medical AI.
title A co-evolving agentic AI system for medical imaging analysis
topic Computer Vision and Pattern Recognition
Quantitative Methods
url https://arxiv.org/abs/2509.20279