Brain PathoGraph Learning

Fuente: arXiv
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Hauptverfasser: Peng, Ciyuan, Le, Nguyen Linh Dan, Jin, Shan, Ding, Dexuan, Yu, Shuo, Xia, Feng
Format: Preprint
Veröffentlicht: 2025
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author Peng, Ciyuan
Le, Nguyen Linh Dan
Jin, Shan
Ding, Dexuan
Yu, Shuo
Xia, Feng
author_facet Peng, Ciyuan
Le, Nguyen Linh Dan
Jin, Shan
Ding, Dexuan
Yu, Shuo
Xia, Feng
contents Brain graph learning has demonstrated significant achievements in the fields of neuroscience and artificial intelligence. However, existing methods struggle to selectively learn disease-related knowledge, leading to heavy parameters and computational costs. This challenge diminishes their efficiency, as well as limits their practicality for real-world clinical applications. To this end, we propose a lightweight Brain PathoGraph Learning (BrainPoG) model that enables efficient brain graph learning by pathological pattern filtering and pathological feature distillation. Specifically, BrainPoG first contains a filter to extract the pathological pattern formulated by highly disease-relevant subgraphs, achieving graph pruning and lesion localization. A PathoGraph is therefore constructed by dropping less disease-relevant subgraphs from the whole brain graph. Afterwards, a pathological feature distillation module is designed to reduce disease-irrelevant noise features and enhance pathological features of each node in the PathoGraph. BrainPoG can exclusively learn informative disease-related knowledge while avoiding less relevant information, achieving efficient brain graph learning. Extensive experiments on four benchmark datasets demonstrate that BrainPoG exhibits superiority in both model performance and computational efficiency across various brain disease detection tasks.
format Preprint
id arxiv_https___arxiv_org_abs_2509_21742
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Brain PathoGraph Learning
Peng, Ciyuan
Le, Nguyen Linh Dan
Jin, Shan
Ding, Dexuan
Yu, Shuo
Xia, Feng
Machine Learning
Artificial Intelligence
Brain graph learning has demonstrated significant achievements in the fields of neuroscience and artificial intelligence. However, existing methods struggle to selectively learn disease-related knowledge, leading to heavy parameters and computational costs. This challenge diminishes their efficiency, as well as limits their practicality for real-world clinical applications. To this end, we propose a lightweight Brain PathoGraph Learning (BrainPoG) model that enables efficient brain graph learning by pathological pattern filtering and pathological feature distillation. Specifically, BrainPoG first contains a filter to extract the pathological pattern formulated by highly disease-relevant subgraphs, achieving graph pruning and lesion localization. A PathoGraph is therefore constructed by dropping less disease-relevant subgraphs from the whole brain graph. Afterwards, a pathological feature distillation module is designed to reduce disease-irrelevant noise features and enhance pathological features of each node in the PathoGraph. BrainPoG can exclusively learn informative disease-related knowledge while avoiding less relevant information, achieving efficient brain graph learning. Extensive experiments on four benchmark datasets demonstrate that BrainPoG exhibits superiority in both model performance and computational efficiency across various brain disease detection tasks.
title Brain PathoGraph Learning
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2509.21742