InfiMed-Foundation: Pioneering Advanced Multimodal Medical Models with Compute-Efficient Pre-Training and Multi-Stage Fine-Tuning

Fuente: arXiv
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Auteurs principaux: Zhu, Guanghao, Hou, Zhitian, Liu, Zeyu, Sang, Zhijie, Xie, Congkai, Yang, Hongxia
Format: Preprint
Publié: 2025
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author Zhu, Guanghao
Hou, Zhitian
Liu, Zeyu
Sang, Zhijie
Xie, Congkai
Yang, Hongxia
author_facet Zhu, Guanghao
Hou, Zhitian
Liu, Zeyu
Sang, Zhijie
Xie, Congkai
Yang, Hongxia
contents Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required for medical tasks, leading to uncertain or hallucinatory responses. Knowledge distillation from advanced models struggles to capture domain-specific expertise in radiology and pharmacology. Additionally, the computational cost of continual pretraining with large-scale medical data poses significant efficiency challenges. To address these issues, we propose InfiMed-Foundation-1.7B and InfiMed-Foundation-4B, two medical-specific MLLMs designed to deliver state-of-the-art performance in medical applications. We combined high-quality general-purpose and medical multimodal data and proposed a novel five-dimensional quality assessment framework to curate high-quality multimodal medical datasets. We employ low-to-high image resolution and multimodal sequence packing to enhance training efficiency, enabling the integration of extensive medical data. Furthermore, a three-stage supervised fine-tuning process ensures effective knowledge extraction for complex medical tasks. Evaluated on the MedEvalKit framework, InfiMed-Foundation-1.7B outperforms Qwen2.5VL-3B, while InfiMed-Foundation-4B surpasses HuatuoGPT-V-7B and MedGemma-27B-IT, demonstrating superior performance in medical visual question answering and diagnostic tasks. By addressing key challenges in data quality, training efficiency, and domain-specific knowledge extraction, our work paves the way for more reliable and effective AI-driven solutions in healthcare. InfiMed-Foundation-4B model is available at \href{https://huggingface.co/InfiX-ai/InfiMed-Foundation-4B}{InfiMed-Foundation-4B}.
format Preprint
id arxiv_https___arxiv_org_abs_2509_22261
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle InfiMed-Foundation: Pioneering Advanced Multimodal Medical Models with Compute-Efficient Pre-Training and Multi-Stage Fine-Tuning
Zhu, Guanghao
Hou, Zhitian
Liu, Zeyu
Sang, Zhijie
Xie, Congkai
Yang, Hongxia
Artificial Intelligence
Computation and Language
Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required for medical tasks, leading to uncertain or hallucinatory responses. Knowledge distillation from advanced models struggles to capture domain-specific expertise in radiology and pharmacology. Additionally, the computational cost of continual pretraining with large-scale medical data poses significant efficiency challenges. To address these issues, we propose InfiMed-Foundation-1.7B and InfiMed-Foundation-4B, two medical-specific MLLMs designed to deliver state-of-the-art performance in medical applications. We combined high-quality general-purpose and medical multimodal data and proposed a novel five-dimensional quality assessment framework to curate high-quality multimodal medical datasets. We employ low-to-high image resolution and multimodal sequence packing to enhance training efficiency, enabling the integration of extensive medical data. Furthermore, a three-stage supervised fine-tuning process ensures effective knowledge extraction for complex medical tasks. Evaluated on the MedEvalKit framework, InfiMed-Foundation-1.7B outperforms Qwen2.5VL-3B, while InfiMed-Foundation-4B surpasses HuatuoGPT-V-7B and MedGemma-27B-IT, demonstrating superior performance in medical visual question answering and diagnostic tasks. By addressing key challenges in data quality, training efficiency, and domain-specific knowledge extraction, our work paves the way for more reliable and effective AI-driven solutions in healthcare. InfiMed-Foundation-4B model is available at \href{https://huggingface.co/InfiX-ai/InfiMed-Foundation-4B}{InfiMed-Foundation-4B}.
title InfiMed-Foundation: Pioneering Advanced Multimodal Medical Models with Compute-Efficient Pre-Training and Multi-Stage Fine-Tuning
topic Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2509.22261