Learning KAN-based Implicit Neural Representations for Deformable Image Registration

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Hauptverfasser: Drozdov, Nikita, Zinovev, Marat, Sorokin, Dmitry
Format: Preprint
Veröffentlicht: 2025
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author Drozdov, Nikita
Zinovev, Marat
Sorokin, Dmitry
author_facet Drozdov, Nikita
Zinovev, Marat
Sorokin, Dmitry
contents Deformable image registration (DIR) is a cornerstone of medical image analysis, enabling spatial alignment for tasks like comparative studies and multi-modal fusion. While learning-based methods (e.g., CNNs, transformers) offer fast inference, they often require large training datasets and struggle to match the precision of classical iterative approaches on some organ types and imaging modalities. Implicit neural representations (INRs) have emerged as a promising alternative, parameterizing deformations as continuous mappings from coordinates to displacement vectors. However, this comes at the cost of requiring instance-specific optimization, making computational efficiency and seed-dependent learning stability critical factors for these methods. In this work, we propose KAN-IDIR and RandKAN-IDIR, the first integration of Kolmogorov-Arnold Networks (KANs) into deformable image registration with implicit neural representations (INRs). Our proposed randomized basis sampling strategy reduces the required number of basis functions in KAN while maintaining registration quality, thereby significantly lowering computational costs. We evaluated our approach on three diverse datasets (lung CT, brain MRI, cardiac MRI) and compared it with competing instance-specific learning-based approaches, dataset-trained deep learning models, and classical registration approaches. KAN-IDIR and RandKAN-IDIR achieved the highest accuracy among INR-based methods across all evaluated modalities and anatomies, with minimal computational overhead and superior learning stability across multiple random seeds. Additionally, we discovered that our RandKAN-IDIR model with randomized basis sampling slightly outperforms the model with learnable basis function indices, while eliminating its additional training-time complexity.
format Preprint
id arxiv_https___arxiv_org_abs_2509_22874
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Learning KAN-based Implicit Neural Representations for Deformable Image Registration
Drozdov, Nikita
Zinovev, Marat
Sorokin, Dmitry
Computer Vision and Pattern Recognition
Deformable image registration (DIR) is a cornerstone of medical image analysis, enabling spatial alignment for tasks like comparative studies and multi-modal fusion. While learning-based methods (e.g., CNNs, transformers) offer fast inference, they often require large training datasets and struggle to match the precision of classical iterative approaches on some organ types and imaging modalities. Implicit neural representations (INRs) have emerged as a promising alternative, parameterizing deformations as continuous mappings from coordinates to displacement vectors. However, this comes at the cost of requiring instance-specific optimization, making computational efficiency and seed-dependent learning stability critical factors for these methods. In this work, we propose KAN-IDIR and RandKAN-IDIR, the first integration of Kolmogorov-Arnold Networks (KANs) into deformable image registration with implicit neural representations (INRs). Our proposed randomized basis sampling strategy reduces the required number of basis functions in KAN while maintaining registration quality, thereby significantly lowering computational costs. We evaluated our approach on three diverse datasets (lung CT, brain MRI, cardiac MRI) and compared it with competing instance-specific learning-based approaches, dataset-trained deep learning models, and classical registration approaches. KAN-IDIR and RandKAN-IDIR achieved the highest accuracy among INR-based methods across all evaluated modalities and anatomies, with minimal computational overhead and superior learning stability across multiple random seeds. Additionally, we discovered that our RandKAN-IDIR model with randomized basis sampling slightly outperforms the model with learnable basis function indices, while eliminating its additional training-time complexity.
title Learning KAN-based Implicit Neural Representations for Deformable Image Registration
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2509.22874