A Computational Perspective on NeuroAI and Synthetic Biological Intelligence

Fuente: arXiv
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Main Authors: Patel, Dhruvik, Tanveer, Md Sayed, Gonzalez-Ferrer, Jesus, Loeffler, Alon, Kagan, Brett J., Mostajo-Radji, Mohammed A., Wang, Ge
Format: Preprint
Published: 2025
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author Patel, Dhruvik
Tanveer, Md Sayed
Gonzalez-Ferrer, Jesus
Loeffler, Alon
Kagan, Brett J.
Mostajo-Radji, Mohammed A.
Wang, Ge
author_facet Patel, Dhruvik
Tanveer, Md Sayed
Gonzalez-Ferrer, Jesus
Loeffler, Alon
Kagan, Brett J.
Mostajo-Radji, Mohammed A.
Wang, Ge
contents NeuroAI is an emerging field at the intersection of neuroscience and artificial intelligence, where insights from brain function guide the design of intelligent systems. A central area within this field is synthetic biological intelligence (SBI), which combines the adaptive learning properties of biological neural networks with engineered hardware and software. SBI systems provide a platform for modeling neural computation, developing biohybrid architectures, and enabling new forms of embodied intelligence. In this review, we organize the NeuroAI landscape into three interacting domains: hardware, software, and wetware. We outline computational frameworks that integrate biological and non-biological systems and highlight recent advances in organoid intelligence, neuromorphic computing, and neuro-symbolic learning. These developments collectively point toward a new class of systems that compute through interactions between living neural tissue and digital algorithms.
format Preprint
id arxiv_https___arxiv_org_abs_2509_23896
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Computational Perspective on NeuroAI and Synthetic Biological Intelligence
Patel, Dhruvik
Tanveer, Md Sayed
Gonzalez-Ferrer, Jesus
Loeffler, Alon
Kagan, Brett J.
Mostajo-Radji, Mohammed A.
Wang, Ge
Neurons and Cognition
Emerging Technologies
Neural and Evolutionary Computing
NeuroAI is an emerging field at the intersection of neuroscience and artificial intelligence, where insights from brain function guide the design of intelligent systems. A central area within this field is synthetic biological intelligence (SBI), which combines the adaptive learning properties of biological neural networks with engineered hardware and software. SBI systems provide a platform for modeling neural computation, developing biohybrid architectures, and enabling new forms of embodied intelligence. In this review, we organize the NeuroAI landscape into three interacting domains: hardware, software, and wetware. We outline computational frameworks that integrate biological and non-biological systems and highlight recent advances in organoid intelligence, neuromorphic computing, and neuro-symbolic learning. These developments collectively point toward a new class of systems that compute through interactions between living neural tissue and digital algorithms.
title A Computational Perspective on NeuroAI and Synthetic Biological Intelligence
topic Neurons and Cognition
Emerging Technologies
Neural and Evolutionary Computing
url https://arxiv.org/abs/2509.23896