Joint Adaptive Penalty for Unbalanced Mediation Pathways

Fuente: arXiv
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Hauptverfasser: Jiang, Hanying, Sankaran, Kris, He, Yinqiu
Format: Preprint
Veröffentlicht: 2025
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author Jiang, Hanying
Sankaran, Kris
He, Yinqiu
author_facet Jiang, Hanying
Sankaran, Kris
He, Yinqiu
contents Mediation analysis has been widely used to investigate how a treatment influences an outcome through intermediate variables, known as mediators. Analyzing a mediation mechanism typically requires assessing multiple model parameters that characterize distinct pathwise effects. Classical methods that estimate these parameters individually can be inefficient, particularly when the underlying pathwise effects exhibit substantial imbalance. To address this challenge, this work proposes a new joint adaptive penalty that integrates information across entire mediation mechanisms, thereby enhancing both parameter estimation and pathway selection. We establish theoretical guarantees for the proposed method under an asymptotic framework and conduct extensive numerical studies to demonstrate its superior performance in scenarios with unbalanced mediation pathways.
format Preprint
id arxiv_https___arxiv_org_abs_2509_25527
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Joint Adaptive Penalty for Unbalanced Mediation Pathways
Jiang, Hanying
Sankaran, Kris
He, Yinqiu
Methodology
Mediation analysis has been widely used to investigate how a treatment influences an outcome through intermediate variables, known as mediators. Analyzing a mediation mechanism typically requires assessing multiple model parameters that characterize distinct pathwise effects. Classical methods that estimate these parameters individually can be inefficient, particularly when the underlying pathwise effects exhibit substantial imbalance. To address this challenge, this work proposes a new joint adaptive penalty that integrates information across entire mediation mechanisms, thereby enhancing both parameter estimation and pathway selection. We establish theoretical guarantees for the proposed method under an asymptotic framework and conduct extensive numerical studies to demonstrate its superior performance in scenarios with unbalanced mediation pathways.
title Joint Adaptive Penalty for Unbalanced Mediation Pathways
topic Methodology
url https://arxiv.org/abs/2509.25527