Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography
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2025
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| author | Descoteaux, Maxime Schilling, Kurt G. Aydogan, Dogu Baran Beaulieu, Christian Borra, Elena Chamberland, Maxime Daducci, Alessandro De Luca, Alberto Dell'Acqua, Flavio Dubois, Jessica Dyrby, Tim B. Farquharson, Shawna Forkel, Stephanie Froeling, Martijn Griffa, Alessandra Grotheer, Mareike Guevara, Pamela Haber, Suzanne N. Jangir, Vinod Kumar Leemans, Alexander Lefebvre, Joel Lin, Ching-Po Little, Graham Lo, Chun-Yi Zac Maffei, Chiara Mayberg, Helen S. McNab, Jennifer A. Mukherjee, Pratik O'Donnell, Lauren J. Parent, Martin Pierpaoli, Carlo Rheault, Francois Rockland, Kathleen S. Roebroeck, Alard Rokem, Ariel Rushmore, R. Jarrett Sarubbo, Silvio Schiavi, Simona Sotiropoulos, Stamatios N Szczupak, Diego de Schotten, Michel Thiebaut Tournier, J-Donald Vergani, Francesco Yang, Joseph Yuan-Mou Zhang, Fan Jones, Derek Petit, Laurent |
| author_facet | Descoteaux, Maxime Schilling, Kurt G. Aydogan, Dogu Baran Beaulieu, Christian Borra, Elena Chamberland, Maxime Daducci, Alessandro De Luca, Alberto Dell'Acqua, Flavio Dubois, Jessica Dyrby, Tim B. Farquharson, Shawna Forkel, Stephanie Froeling, Martijn Griffa, Alessandra Grotheer, Mareike Guevara, Pamela Haber, Suzanne N. Jangir, Vinod Kumar Leemans, Alexander Lefebvre, Joel Lin, Ching-Po Little, Graham Lo, Chun-Yi Zac Maffei, Chiara Mayberg, Helen S. McNab, Jennifer A. Mukherjee, Pratik O'Donnell, Lauren J. Parent, Martin Pierpaoli, Carlo Rheault, Francois Rockland, Kathleen S. Roebroeck, Alard Rokem, Ariel Rushmore, R. Jarrett Sarubbo, Silvio Schiavi, Simona Sotiropoulos, Stamatios N Szczupak, Diego de Schotten, Michel Thiebaut Tournier, J-Donald Vergani, Francesco Yang, Joseph Yuan-Mou Zhang, Fan Jones, Derek Petit, Laurent |
| contents | In the spirit of the historic Millennium Prize Problems that heralded a new era for mathematics, the newly formed International Society for Tractography (IST) has launched the Millennium Pathways for Tractography, a community-driven roadmap designed to shape the future of the field. Conceived during the inaugural Tract-Anat Retreat, this initiative reflects a collective vision for advancing tractography over the coming decade and beyond. The roadmap consists of 40 grand challenges, developed by international experts and organized into seven categories spanning three overarching themes: neuroanatomy, tractography methods, and clinical applications. By defining shared short-, medium-, and long-term goals, these pathways provide a structured framework to confront fundamental limitations, promote rigorous validation, and accelerate the translation of tractography into a robust tool for neuroscience and medicine. Ultimately, the Millennium Pathways aim to guide and inspire future research and collaboration, ensuring the continued scientific and clinical relevance of tractography well into the future. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2509_26259 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography Descoteaux, Maxime Schilling, Kurt G. Aydogan, Dogu Baran Beaulieu, Christian Borra, Elena Chamberland, Maxime Daducci, Alessandro De Luca, Alberto Dell'Acqua, Flavio Dubois, Jessica Dyrby, Tim B. Farquharson, Shawna Forkel, Stephanie Froeling, Martijn Griffa, Alessandra Grotheer, Mareike Guevara, Pamela Haber, Suzanne N. Jangir, Vinod Kumar Leemans, Alexander Lefebvre, Joel Lin, Ching-Po Little, Graham Lo, Chun-Yi Zac Maffei, Chiara Mayberg, Helen S. McNab, Jennifer A. Mukherjee, Pratik O'Donnell, Lauren J. Parent, Martin Pierpaoli, Carlo Rheault, Francois Rockland, Kathleen S. Roebroeck, Alard Rokem, Ariel Rushmore, R. Jarrett Sarubbo, Silvio Schiavi, Simona Sotiropoulos, Stamatios N Szczupak, Diego de Schotten, Michel Thiebaut Tournier, J-Donald Vergani, Francesco Yang, Joseph Yuan-Mou Zhang, Fan Jones, Derek Petit, Laurent Medical Physics Tissues and Organs In the spirit of the historic Millennium Prize Problems that heralded a new era for mathematics, the newly formed International Society for Tractography (IST) has launched the Millennium Pathways for Tractography, a community-driven roadmap designed to shape the future of the field. Conceived during the inaugural Tract-Anat Retreat, this initiative reflects a collective vision for advancing tractography over the coming decade and beyond. The roadmap consists of 40 grand challenges, developed by international experts and organized into seven categories spanning three overarching themes: neuroanatomy, tractography methods, and clinical applications. By defining shared short-, medium-, and long-term goals, these pathways provide a structured framework to confront fundamental limitations, promote rigorous validation, and accelerate the translation of tractography into a robust tool for neuroscience and medicine. Ultimately, the Millennium Pathways aim to guide and inspire future research and collaboration, ensuring the continued scientific and clinical relevance of tractography well into the future. |
| title | Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography |
| topic | Medical Physics Tissues and Organs |
| url | https://arxiv.org/abs/2509.26259 |