Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences

Fuente: arXiv
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Autore principale: Weissman, Michael B.
Natura: Preprint
Pubblicazione: 2025
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author Weissman, Michael B.
author_facet Weissman, Michael B.
contents A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to humans had occurred than that just one had. Here I show that after correcting a fundamental error in Bayesian reasoning the results in that paper give larger likelihood for a single introduction than for two.
format Preprint
id arxiv_https___arxiv_org_abs_2510_01484
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
Weissman, Michael B.
Populations and Evolution
Quantitative Methods
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to humans had occurred than that just one had. Here I show that after correcting a fundamental error in Bayesian reasoning the results in that paper give larger likelihood for a single introduction than for two.
title Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
topic Populations and Evolution
Quantitative Methods
url https://arxiv.org/abs/2510.01484