Robust Classification of Oral Cancer with Limited Training Data

Fuente: arXiv
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Main Authors: Sonawane, Akshay Bhagwan, Swamikannan, Lena D., Tamil, Lakshman
Format: Preprint
Published: 2025
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author Sonawane, Akshay Bhagwan
Swamikannan, Lena D.
Tamil, Lakshman
author_facet Sonawane, Akshay Bhagwan
Swamikannan, Lena D.
Tamil, Lakshman
contents Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to limited oral health programs, inadequate infrastructure, and a shortage of healthcare practitioners. Conventional deep learning models, while promising, often rely on point estimates, leading to overconfidence and reduced reliability. Critically, these models require large datasets to mitigate overfitting and ensure generalizability, an unrealistic demand in settings with limited training data. To address these issues, we propose a hybrid model that combines a convolutional neural network (CNN) with Bayesian deep learning for oral cancer classification using small training sets. This approach employs variational inference to enhance reliability through uncertainty quantification. The model was trained on photographic color images captured by smartphones and evaluated on three distinct test datasets. The proposed method achieved 94% accuracy on a test dataset with a distribution similar to that of the training data, comparable to traditional CNN performance. Notably, for real-world photographic image data, despite limitations and variations differing from the training dataset, the proposed model demonstrated superior generalizability, achieving 88% accuracy on diverse datasets compared to 72.94% for traditional CNNs, even with a smaller dataset. Confidence analysis revealed that the model exhibits low uncertainty (high confidence) for correctly classified samples and high uncertainty (low confidence) for misclassified samples. These results underscore the effectiveness of Bayesian inference in data-scarce environments in enhancing early oral cancer diagnosis by improving model reliability and generalizability.
format Preprint
id arxiv_https___arxiv_org_abs_2510_01547
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Robust Classification of Oral Cancer with Limited Training Data
Sonawane, Akshay Bhagwan
Swamikannan, Lena D.
Tamil, Lakshman
Computer Vision and Pattern Recognition
Machine Learning
Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to limited oral health programs, inadequate infrastructure, and a shortage of healthcare practitioners. Conventional deep learning models, while promising, often rely on point estimates, leading to overconfidence and reduced reliability. Critically, these models require large datasets to mitigate overfitting and ensure generalizability, an unrealistic demand in settings with limited training data. To address these issues, we propose a hybrid model that combines a convolutional neural network (CNN) with Bayesian deep learning for oral cancer classification using small training sets. This approach employs variational inference to enhance reliability through uncertainty quantification. The model was trained on photographic color images captured by smartphones and evaluated on three distinct test datasets. The proposed method achieved 94% accuracy on a test dataset with a distribution similar to that of the training data, comparable to traditional CNN performance. Notably, for real-world photographic image data, despite limitations and variations differing from the training dataset, the proposed model demonstrated superior generalizability, achieving 88% accuracy on diverse datasets compared to 72.94% for traditional CNNs, even with a smaller dataset. Confidence analysis revealed that the model exhibits low uncertainty (high confidence) for correctly classified samples and high uncertainty (low confidence) for misclassified samples. These results underscore the effectiveness of Bayesian inference in data-scarce environments in enhancing early oral cancer diagnosis by improving model reliability and generalizability.
title Robust Classification of Oral Cancer with Limited Training Data
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2510.01547