Detection of Chagas Disease from the ECG: The George B. Moody PhysioNet Challenge 2025

Fuente: arXiv
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Autori principali: Reyna, Matthew A., Koscova, Zuzana, Pavlus, Jan, Saghafi, Soheil, Weigle, James, Elola, Andoni, Seyedi, Salman, Campbell, Kiersten, Li, Qiao, Rad, Ali Bahrami, Ribeiro, Antônio H., Ribeiro, Antonio Luiz P., Sameni, Reza, Clifford, Gari D.
Natura: Preprint
Pubblicazione: 2025
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author Reyna, Matthew A.
Koscova, Zuzana
Pavlus, Jan
Saghafi, Soheil
Weigle, James
Elola, Andoni
Seyedi, Salman
Campbell, Kiersten
Li, Qiao
Rad, Ali Bahrami
Ribeiro, Antônio H.
Ribeiro, Antonio Luiz P.
Sameni, Reza
Clifford, Gari D.
author_facet Reyna, Matthew A.
Koscova, Zuzana
Pavlus, Jan
Saghafi, Soheil
Weigle, James
Elola, Andoni
Seyedi, Salman
Campbell, Kiersten
Li, Qiao
Rad, Ali Bahrami
Ribeiro, Antônio H.
Ribeiro, Antonio Luiz P.
Sameni, Reza
Clifford, Gari D.
contents Objective: Chagas disease is a parasitic infection that is endemic to South America, Central America, and, more recently, the U.S., primarily transmitted by insects. Chronic Chagas disease can cause cardiovascular diseases and digestive problems. Serological testing capacities for Chagas disease are limited, but Chagas cardiomyopathy often manifests in ECGs, providing an opportunity to prioritize patients for testing and treatment. Approach: The George B. Moody PhysioNet Challenge 2025 invites teams to develop algorithmic approaches for identifying Chagas disease from electrocardiograms (ECGs). Main results: This Challenge provides multiple innovations. First, we leveraged several datasets with labels from patient reports and serological testing, provided a large dataset with weak labels and smaller datasets with strong labels. Second, we augmented the data to support model robustness and generalizability to unseen data sources. Third, we applied an evaluation metric that captured the local serological testing capacity for Chagas disease to frame the machine learning problem as a triage task. Significance: Over 630 participants from 111 teams submitted over 1300 entries during the Challenge, representing diverse approaches from academia and industry worldwide.
format Preprint
id arxiv_https___arxiv_org_abs_2510_02202
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Detection of Chagas Disease from the ECG: The George B. Moody PhysioNet Challenge 2025
Reyna, Matthew A.
Koscova, Zuzana
Pavlus, Jan
Saghafi, Soheil
Weigle, James
Elola, Andoni
Seyedi, Salman
Campbell, Kiersten
Li, Qiao
Rad, Ali Bahrami
Ribeiro, Antônio H.
Ribeiro, Antonio Luiz P.
Sameni, Reza
Clifford, Gari D.
Machine Learning
Artificial Intelligence
68Txx
Objective: Chagas disease is a parasitic infection that is endemic to South America, Central America, and, more recently, the U.S., primarily transmitted by insects. Chronic Chagas disease can cause cardiovascular diseases and digestive problems. Serological testing capacities for Chagas disease are limited, but Chagas cardiomyopathy often manifests in ECGs, providing an opportunity to prioritize patients for testing and treatment. Approach: The George B. Moody PhysioNet Challenge 2025 invites teams to develop algorithmic approaches for identifying Chagas disease from electrocardiograms (ECGs). Main results: This Challenge provides multiple innovations. First, we leveraged several datasets with labels from patient reports and serological testing, provided a large dataset with weak labels and smaller datasets with strong labels. Second, we augmented the data to support model robustness and generalizability to unseen data sources. Third, we applied an evaluation metric that captured the local serological testing capacity for Chagas disease to frame the machine learning problem as a triage task. Significance: Over 630 participants from 111 teams submitted over 1300 entries during the Challenge, representing diverse approaches from academia and industry worldwide.
title Detection of Chagas Disease from the ECG: The George B. Moody PhysioNet Challenge 2025
topic Machine Learning
Artificial Intelligence
68Txx
url https://arxiv.org/abs/2510.02202