Skin Lesion Classification Based on ResNet-50 Enhanced With Adaptive Spatial Feature Fusion
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arXiv
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| Autori principali: | , , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2025
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| _version_ | 1866916062645190656 |
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| author | Liu, Runhao Zha, Fengyi Ding, Fei Yao, Guangzhen Zhang, Peng |
| author_facet | Liu, Runhao Zha, Fengyi Ding, Fei Yao, Guangzhen Zhang, Peng |
| contents | Skin cancer classification is challenging due to high inter-class similarity, intra-class variability, and artifacts in dermoscopic images. To address these issues, we propose an improved ResNet-50 with Adaptive Spatial Feature Fusion (ASFF), which adaptively integrates multi-scale semantic and surface features to refine representations and reduce overfitting. The ResNet-50 model is enhanced with an adaptive feature fusion mechanism to achieve more effective multi-scale feature extraction and improve overall performance. Specifically, a dual-branch design fuses high-level semantic and mid-level detail features which use global average pooling and fully connected layers to produce spatial weights, and emphasizes lesion-relevant regions. Evaluated on a balanced subset of ISIC 2020 (3,297 images, randomly selected from the original dataset), the ASFF-based ResNet-50 outperforms multiple CNN baselines, achieving 93.182% accuracy with superior precision, recall, specificity, and F1. It also reaches 0.9670 AUC (P-R) and 0.9717 AUC (ROC). Grad-CAM visualizations show more accurate focus on lesion areas.The proposed model also generalizes well to ISIC 2019 external validation, outperforming the ResNet-50 baseline. These findings demonstrate that the proposed approach provides a more effective and efficient solution for computer-aided skin cancer diagnosis. The generation codes, weights and confusion matrices are open sourced in https://github.com/Grapesea/ASFF-ResNet50-enhanced. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2510_03876 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Skin Lesion Classification Based on ResNet-50 Enhanced With Adaptive Spatial Feature Fusion Liu, Runhao Zha, Fengyi Ding, Fei Yao, Guangzhen Zhang, Peng Computer Vision and Pattern Recognition Skin cancer classification is challenging due to high inter-class similarity, intra-class variability, and artifacts in dermoscopic images. To address these issues, we propose an improved ResNet-50 with Adaptive Spatial Feature Fusion (ASFF), which adaptively integrates multi-scale semantic and surface features to refine representations and reduce overfitting. The ResNet-50 model is enhanced with an adaptive feature fusion mechanism to achieve more effective multi-scale feature extraction and improve overall performance. Specifically, a dual-branch design fuses high-level semantic and mid-level detail features which use global average pooling and fully connected layers to produce spatial weights, and emphasizes lesion-relevant regions. Evaluated on a balanced subset of ISIC 2020 (3,297 images, randomly selected from the original dataset), the ASFF-based ResNet-50 outperforms multiple CNN baselines, achieving 93.182% accuracy with superior precision, recall, specificity, and F1. It also reaches 0.9670 AUC (P-R) and 0.9717 AUC (ROC). Grad-CAM visualizations show more accurate focus on lesion areas.The proposed model also generalizes well to ISIC 2019 external validation, outperforming the ResNet-50 baseline. These findings demonstrate that the proposed approach provides a more effective and efficient solution for computer-aided skin cancer diagnosis. The generation codes, weights and confusion matrices are open sourced in https://github.com/Grapesea/ASFF-ResNet50-enhanced. |
| title | Skin Lesion Classification Based on ResNet-50 Enhanced With Adaptive Spatial Feature Fusion |
| topic | Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2510.03876 |