Evaluation of Clinical Trials Reporting Quality using Large Language Models

Fuente: arXiv
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Main Authors: Laï-king, Mathieu, Paroubek, Patrick
Format: Preprint
Published: 2025
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author Laï-king, Mathieu
Paroubek, Patrick
author_facet Laï-king, Mathieu
Paroubek, Patrick
contents Reporting quality is an important topic in clinical trial research articles, as it can impact clinical decisions. In this article, we test the ability of large language models to assess the reporting quality of this type of article using the Consolidated Standards of Reporting Trials (CONSORT). We create CONSORT-QA, an evaluation corpus from two studies on abstract reporting quality with CONSORT-abstract standards. We then evaluate the ability of different large generative language models (from the general domain or adapted to the biomedical domain) to correctly assess CONSORT criteria with different known prompting methods, including Chain-of-thought. Our best combination of model and prompting method achieves 85% accuracy. Using Chain-of-thought adds valuable information on the model's reasoning for completing the task.
format Preprint
id arxiv_https___arxiv_org_abs_2510_04338
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Evaluation of Clinical Trials Reporting Quality using Large Language Models
Laï-king, Mathieu
Paroubek, Patrick
Computation and Language
Reporting quality is an important topic in clinical trial research articles, as it can impact clinical decisions. In this article, we test the ability of large language models to assess the reporting quality of this type of article using the Consolidated Standards of Reporting Trials (CONSORT). We create CONSORT-QA, an evaluation corpus from two studies on abstract reporting quality with CONSORT-abstract standards. We then evaluate the ability of different large generative language models (from the general domain or adapted to the biomedical domain) to correctly assess CONSORT criteria with different known prompting methods, including Chain-of-thought. Our best combination of model and prompting method achieves 85% accuracy. Using Chain-of-thought adds valuable information on the model's reasoning for completing the task.
title Evaluation of Clinical Trials Reporting Quality using Large Language Models
topic Computation and Language
url https://arxiv.org/abs/2510.04338