Forecasting-based Biomedical Time-series Data Synthesis for Open Data and Robust AI

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Hauptverfasser: Lee, Youngjoon, Cho, Seongmin, Jo, Yehhyun, Gong, Jinu, Lee, Hyunjoo Jenny, Kang, Joonhyuk
Format: Preprint
Veröffentlicht: 2025
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author Lee, Youngjoon
Cho, Seongmin
Jo, Yehhyun
Gong, Jinu
Lee, Hyunjoo Jenny
Kang, Joonhyuk
author_facet Lee, Youngjoon
Cho, Seongmin
Jo, Yehhyun
Gong, Jinu
Lee, Hyunjoo Jenny
Kang, Joonhyuk
contents The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic data generation presents a promising solution by producing artificial datasets that maintain the statistical properties of real biomedical time-series data without compromising patient confidentiality. While GANs, VAEs, and diffusion models capture global data distributions, forecasting models offer inductive biases tailored for sequential dynamics. We propose a framework for synthetic biomedical time-series data generation based on recent forecasting models that accurately replicates complex electrophysiological signals such as EEG and EMG with high fidelity. These synthetic datasets can be freely shared for open AI development and consistently improve downstream model performance. Numerical results on sleep-stage classification show up to a 3.71\% performance gain with augmentation and a 91.00\% synthetic-only accuracy that surpasses the real-data-only baseline.
format Preprint
id arxiv_https___arxiv_org_abs_2510_04622
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Forecasting-based Biomedical Time-series Data Synthesis for Open Data and Robust AI
Lee, Youngjoon
Cho, Seongmin
Jo, Yehhyun
Gong, Jinu
Lee, Hyunjoo Jenny
Kang, Joonhyuk
Machine Learning
Signal Processing
The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic data generation presents a promising solution by producing artificial datasets that maintain the statistical properties of real biomedical time-series data without compromising patient confidentiality. While GANs, VAEs, and diffusion models capture global data distributions, forecasting models offer inductive biases tailored for sequential dynamics. We propose a framework for synthetic biomedical time-series data generation based on recent forecasting models that accurately replicates complex electrophysiological signals such as EEG and EMG with high fidelity. These synthetic datasets can be freely shared for open AI development and consistently improve downstream model performance. Numerical results on sleep-stage classification show up to a 3.71\% performance gain with augmentation and a 91.00\% synthetic-only accuracy that surpasses the real-data-only baseline.
title Forecasting-based Biomedical Time-series Data Synthesis for Open Data and Robust AI
topic Machine Learning
Signal Processing
url https://arxiv.org/abs/2510.04622