Missing Data Imputation in the Context of Propensity Score Analysis: A Systematic Review

Fuente: arXiv
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Autores principales: Garayemi, Saghar, Khoei, Reza Ali Akbari, Friedrich, Sarah
Formato: Preprint
Publicado: 2025
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author Garayemi, Saghar
Khoei, Reza Ali Akbari
Friedrich, Sarah
author_facet Garayemi, Saghar
Khoei, Reza Ali Akbari
Friedrich, Sarah
contents Missing data is a common challenge in observational studies. Another challenge stems from the observational nature of the study itself. Here, propensity score analysis can be used as a technique to replicate conditions similar to those found in clinical trials. With regard to the missing data, a majority of studies only analyze the complete cases, but this has several pitfalls. In this review, we investigate which methods are used for the handling of missing data in the context of propensity score analyses. Therefore, we searched PubMed for the keywords propensity score and missing data, restricting our search to the time between January 2010 and February 2024. The PRISMA statement was followed in this review. A total of 147 articles were included in the analyses. A major finding of this study is that although the usage of multiple imputation (MI) has risen over time, only a limited number of studies describe the mechanism of missing data and the details of the MI algorithm. Keywords Missing data, Propensity Score, Observational Data, Multiple Imputation, Systematic Review
format Preprint
id arxiv_https___arxiv_org_abs_2510_05857
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Missing Data Imputation in the Context of Propensity Score Analysis: A Systematic Review
Garayemi, Saghar
Khoei, Reza Ali Akbari
Friedrich, Sarah
Other Statistics
Missing data is a common challenge in observational studies. Another challenge stems from the observational nature of the study itself. Here, propensity score analysis can be used as a technique to replicate conditions similar to those found in clinical trials. With regard to the missing data, a majority of studies only analyze the complete cases, but this has several pitfalls. In this review, we investigate which methods are used for the handling of missing data in the context of propensity score analyses. Therefore, we searched PubMed for the keywords propensity score and missing data, restricting our search to the time between January 2010 and February 2024. The PRISMA statement was followed in this review. A total of 147 articles were included in the analyses. A major finding of this study is that although the usage of multiple imputation (MI) has risen over time, only a limited number of studies describe the mechanism of missing data and the details of the MI algorithm. Keywords Missing data, Propensity Score, Observational Data, Multiple Imputation, Systematic Review
title Missing Data Imputation in the Context of Propensity Score Analysis: A Systematic Review
topic Other Statistics
url https://arxiv.org/abs/2510.05857