The Feasibility of Acoustophoresis Multimodal Control

Fuente: arXiv
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Main Authors: Perticarari, Guilherme, Wu, Dongjun, Baasch, Thierry
Format: Preprint
Published: 2025
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author Perticarari, Guilherme
Wu, Dongjun
Baasch, Thierry
author_facet Perticarari, Guilherme
Wu, Dongjun
Baasch, Thierry
contents Actuating the acoustic resonance modes of a microfluidic device containing suspended particles (e.g., cells) allows for the manipulation of their individual positions. In this work, we investigate how the number of resonance modes $M$ chosen for actuation and the number of particles $P$ affect the probability of success $S$ of manipulation tasks, denoted Acoustophoretic Control Problems (ACPs). Using simulations, we show that the ratio of locally controllable volume to the state-space volume correlates strongly with $S$. This ratio can be efficiently computed from the pressure field geometry as it does not involve solving a control problem, thus opening possibilities for experimental and numerical device optimization routines. Further, we show numerically that in noise-free 1D systems $S \approx 1 - P/M$, and that in noisy 1D and 2D systems $S$ is accurately predicted by Wendel's Theorem. We also show that the relationship between $M$ and $P$ for a given $S$ is approximately linear, suggesting that as long as $P/M$ is constant, $S$ will remain unchanged. We validate this finding by successfully simulating the control of systems with up to $60$ particles with up to $600$ modes.
format Preprint
id arxiv_https___arxiv_org_abs_2510_06116
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle The Feasibility of Acoustophoresis Multimodal Control
Perticarari, Guilherme
Wu, Dongjun
Baasch, Thierry
Applied Physics
Classical Physics
Actuating the acoustic resonance modes of a microfluidic device containing suspended particles (e.g., cells) allows for the manipulation of their individual positions. In this work, we investigate how the number of resonance modes $M$ chosen for actuation and the number of particles $P$ affect the probability of success $S$ of manipulation tasks, denoted Acoustophoretic Control Problems (ACPs). Using simulations, we show that the ratio of locally controllable volume to the state-space volume correlates strongly with $S$. This ratio can be efficiently computed from the pressure field geometry as it does not involve solving a control problem, thus opening possibilities for experimental and numerical device optimization routines. Further, we show numerically that in noise-free 1D systems $S \approx 1 - P/M$, and that in noisy 1D and 2D systems $S$ is accurately predicted by Wendel's Theorem. We also show that the relationship between $M$ and $P$ for a given $S$ is approximately linear, suggesting that as long as $P/M$ is constant, $S$ will remain unchanged. We validate this finding by successfully simulating the control of systems with up to $60$ particles with up to $600$ modes.
title The Feasibility of Acoustophoresis Multimodal Control
topic Applied Physics
Classical Physics
url https://arxiv.org/abs/2510.06116