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Main Authors: Tang, Fenghe, Dong, Chengqi, Ma, Wenxin, Xu, Zikang, Zhu, Heqin, Jiang, Zihang, Wang, Rongsheng, Wang, Yuhao, Wu, Chenxu, Zhou, Shaohua Kevin
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2510.07041
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author Tang, Fenghe
Dong, Chengqi
Ma, Wenxin
Xu, Zikang
Zhu, Heqin
Jiang, Zihang
Wang, Rongsheng
Wang, Yuhao
Wu, Chenxu
Zhou, Shaohua Kevin
author_facet Tang, Fenghe
Dong, Chengqi
Ma, Wenxin
Xu, Zikang
Zhu, Heqin
Jiang, Zihang
Wang, Rongsheng
Wang, Yuhao
Wu, Chenxu
Zhou, Shaohua Kevin
contents Over the past decade, U-Net has been the dominant architecture in medical image segmentation, leading to the development of thousands of U-shaped variants. Despite its widespread adoption, there is still no comprehensive benchmark to systematically evaluate their performance and utility, largely because of insufficient statistical validation and limited consideration of efficiency and generalization across diverse datasets. To bridge this gap, we present U-Bench, the first large-scale, statistically rigorous benchmark that evaluates 100 U-Net variants across 28 datasets and 10 imaging modalities. Our contributions are threefold: (1) Comprehensive Evaluation: U-Bench evaluates models along three key dimensions: statistical robustness, zero-shot generalization, and computational efficiency. We introduce a novel metric, U-Score, which jointly captures the performance-efficiency trade-off, offering a deployment-oriented perspective on model progress. (2) Systematic Analysis and Model Selection Guidance: We summarize key findings from the large-scale evaluation and systematically analyze the impact of dataset characteristics and architectural paradigms on model performance. Based on these insights, we propose a model advisor agent to guide researchers in selecting the most suitable models for specific datasets and tasks. (3) Public Availability: We provide all code, models, protocols, and weights, enabling the community to reproduce our results and extend the benchmark with future methods. In summary, U-Bench not only exposes gaps in previous evaluations but also establishes a foundation for fair, reproducible, and practically relevant benchmarking in the next decade of U-Net-based segmentation models. The project can be accessed at: https://fenghetan9.github.io/ubench. Code is available at: https://github.com/FengheTan9/U-Bench.
format Preprint
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institution arXiv
publishDate 2025
record_format arxiv
spellingShingle U-Bench: A Comprehensive Understanding of U-Net through 100-Variant Benchmarking
Tang, Fenghe
Dong, Chengqi
Ma, Wenxin
Xu, Zikang
Zhu, Heqin
Jiang, Zihang
Wang, Rongsheng
Wang, Yuhao
Wu, Chenxu
Zhou, Shaohua Kevin
Computer Vision and Pattern Recognition
Over the past decade, U-Net has been the dominant architecture in medical image segmentation, leading to the development of thousands of U-shaped variants. Despite its widespread adoption, there is still no comprehensive benchmark to systematically evaluate their performance and utility, largely because of insufficient statistical validation and limited consideration of efficiency and generalization across diverse datasets. To bridge this gap, we present U-Bench, the first large-scale, statistically rigorous benchmark that evaluates 100 U-Net variants across 28 datasets and 10 imaging modalities. Our contributions are threefold: (1) Comprehensive Evaluation: U-Bench evaluates models along three key dimensions: statistical robustness, zero-shot generalization, and computational efficiency. We introduce a novel metric, U-Score, which jointly captures the performance-efficiency trade-off, offering a deployment-oriented perspective on model progress. (2) Systematic Analysis and Model Selection Guidance: We summarize key findings from the large-scale evaluation and systematically analyze the impact of dataset characteristics and architectural paradigms on model performance. Based on these insights, we propose a model advisor agent to guide researchers in selecting the most suitable models for specific datasets and tasks. (3) Public Availability: We provide all code, models, protocols, and weights, enabling the community to reproduce our results and extend the benchmark with future methods. In summary, U-Bench not only exposes gaps in previous evaluations but also establishes a foundation for fair, reproducible, and practically relevant benchmarking in the next decade of U-Net-based segmentation models. The project can be accessed at: https://fenghetan9.github.io/ubench. Code is available at: https://github.com/FengheTan9/U-Bench.
title U-Bench: A Comprehensive Understanding of U-Net through 100-Variant Benchmarking
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2510.07041