RASALoRE: Region Aware Spatial Attention with Location-based Random Embeddings for Weakly Supervised Anomaly Detection in Brain MRI Scans

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Main Authors: Sharma, Bheeshm, Jaganathan, Karthikeyan, Palaniappan, Balamurugan
Format: Preprint
Published: 2025
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author Sharma, Bheeshm
Jaganathan, Karthikeyan
Palaniappan, Balamurugan
author_facet Sharma, Bheeshm
Jaganathan, Karthikeyan
Palaniappan, Balamurugan
contents Weakly Supervised Anomaly detection (WSAD) in brain MRI scans is an important challenge useful to obtain quick and accurate detection of brain anomalies when precise pixel-level anomaly annotations are unavailable and only weak labels (e.g., slice-level) are available. In this work, we propose RASALoRE: Region Aware Spatial Attention with Location-based Random Embeddings, a novel two-stage WSAD framework. In the first stage, we introduce a Discriminative Dual Prompt Tuning (DDPT) mechanism that generates high-quality pseudo weak masks based on slice-level labels, serving as coarse localization cues. In the second stage, we propose a segmentation network with a region-aware spatial attention mechanism that relies on fixed location-based random embeddings. This design enables the model to effectively focus on anomalous regions. Our approach achieves state-of-the-art anomaly detection performance, significantly outperforming existing WSAD methods while utilizing less than 8 million parameters. Extensive evaluations on the BraTS20, BraTS21, BraTS23, and MSD datasets demonstrate a substantial performance improvement coupled with a significant reduction in computational complexity. Code is available at: https://github.com/BheeshmSharma/RASALoRE-BMVC-2025/.
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publishDate 2025
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spellingShingle RASALoRE: Region Aware Spatial Attention with Location-based Random Embeddings for Weakly Supervised Anomaly Detection in Brain MRI Scans
Sharma, Bheeshm
Jaganathan, Karthikeyan
Palaniappan, Balamurugan
Computer Vision and Pattern Recognition
Weakly Supervised Anomaly detection (WSAD) in brain MRI scans is an important challenge useful to obtain quick and accurate detection of brain anomalies when precise pixel-level anomaly annotations are unavailable and only weak labels (e.g., slice-level) are available. In this work, we propose RASALoRE: Region Aware Spatial Attention with Location-based Random Embeddings, a novel two-stage WSAD framework. In the first stage, we introduce a Discriminative Dual Prompt Tuning (DDPT) mechanism that generates high-quality pseudo weak masks based on slice-level labels, serving as coarse localization cues. In the second stage, we propose a segmentation network with a region-aware spatial attention mechanism that relies on fixed location-based random embeddings. This design enables the model to effectively focus on anomalous regions. Our approach achieves state-of-the-art anomaly detection performance, significantly outperforming existing WSAD methods while utilizing less than 8 million parameters. Extensive evaluations on the BraTS20, BraTS21, BraTS23, and MSD datasets demonstrate a substantial performance improvement coupled with a significant reduction in computational complexity. Code is available at: https://github.com/BheeshmSharma/RASALoRE-BMVC-2025/.
title RASALoRE: Region Aware Spatial Attention with Location-based Random Embeddings for Weakly Supervised Anomaly Detection in Brain MRI Scans
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2510.08052