FedL2T: Personalized Federated Learning with Two-Teacher Distillation for Seizure Prediction

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Hauptverfasser: Lou, Jionghao, Zhang, Jian, Li, Zhongmei, Chen, Lanlan, Feng, Enbo
Format: Preprint
Veröffentlicht: 2025
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author Lou, Jionghao
Zhang, Jian
Li, Zhongmei
Chen, Lanlan
Feng, Enbo
author_facet Lou, Jionghao
Zhang, Jian
Li, Zhongmei
Chen, Lanlan
Feng, Enbo
contents The training of deep learning models in seizure prediction requires large amounts of Electroencephalogram (EEG) data. However, acquiring sufficient labeled EEG data is difficult due to annotation costs and privacy constraints. Federated Learning (FL) enables privacy-preserving collaborative training by sharing model updates instead of raw data. However, due to the inherent inter-patient variability in real-world scenarios, existing FL-based seizure prediction methods struggle to achieve robust performance under heterogeneous client settings. To address this challenge, we propose FedL2T, a personalized federated learning framework that leverages a novel two-teacher knowledge distillation strategy to generate superior personalized models for each client. Specifically, each client simultaneously learns from a globally aggregated model and a dynamically assigned peer model, promoting more direct and enriched knowledge exchange. To ensure reliable knowledge transfer, FedL2T employs an adaptive multi-level distillation strategy that aligns both prediction outputs and intermediate feature representations based on task confidence. In addition, a proximal regularization term is introduced to constrain personalized model updates, thereby enhancing training stability. Extensive experiments on two EEG datasets demonstrate that FedL2T consistently outperforms state-of-the-art FL methods, particularly under low-label conditions. Moreover, FedL2T exhibits rapid and stable convergence toward optimal performance, thereby reducing the number of communication rounds and associated overhead. These results underscore the potential of FedL2T as a reliable and personalized solution for seizure prediction in privacy-sensitive healthcare scenarios.
format Preprint
id arxiv_https___arxiv_org_abs_2510_08984
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle FedL2T: Personalized Federated Learning with Two-Teacher Distillation for Seizure Prediction
Lou, Jionghao
Zhang, Jian
Li, Zhongmei
Chen, Lanlan
Feng, Enbo
Machine Learning
Neural and Evolutionary Computing
The training of deep learning models in seizure prediction requires large amounts of Electroencephalogram (EEG) data. However, acquiring sufficient labeled EEG data is difficult due to annotation costs and privacy constraints. Federated Learning (FL) enables privacy-preserving collaborative training by sharing model updates instead of raw data. However, due to the inherent inter-patient variability in real-world scenarios, existing FL-based seizure prediction methods struggle to achieve robust performance under heterogeneous client settings. To address this challenge, we propose FedL2T, a personalized federated learning framework that leverages a novel two-teacher knowledge distillation strategy to generate superior personalized models for each client. Specifically, each client simultaneously learns from a globally aggregated model and a dynamically assigned peer model, promoting more direct and enriched knowledge exchange. To ensure reliable knowledge transfer, FedL2T employs an adaptive multi-level distillation strategy that aligns both prediction outputs and intermediate feature representations based on task confidence. In addition, a proximal regularization term is introduced to constrain personalized model updates, thereby enhancing training stability. Extensive experiments on two EEG datasets demonstrate that FedL2T consistently outperforms state-of-the-art FL methods, particularly under low-label conditions. Moreover, FedL2T exhibits rapid and stable convergence toward optimal performance, thereby reducing the number of communication rounds and associated overhead. These results underscore the potential of FedL2T as a reliable and personalized solution for seizure prediction in privacy-sensitive healthcare scenarios.
title FedL2T: Personalized Federated Learning with Two-Teacher Distillation for Seizure Prediction
topic Machine Learning
Neural and Evolutionary Computing
url https://arxiv.org/abs/2510.08984