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Main Authors: Kurz, Wolfgang, Baranes, Danny
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2510.10286
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author Kurz, Wolfgang
Baranes, Danny
author_facet Kurz, Wolfgang
Baranes, Danny
contents Building on evidence of structural parallels between brain networks and the cosmic web [1], we apply AI-based geometric analysis to cultured neuronal networks. Isolated neurons self-organize into dendritic lattices shaped by reproducible wiring rules. These lattices show non-random features-frequent dendritic convergence, hub nodes, small-world connectivity, and large voids. Synaptic contacts cluster and strengthen at hubs. Strikingly, these properties mirror the cosmic web: dendritic branches resemble cosmic filaments and synapses map to galaxies. Quantitative metrics align across systems, suggesting shared underlying geometric principles. We invite cross-disciplinary collaboration to interrogate and extend these parallels.
format Preprint
id arxiv_https___arxiv_org_abs_2510_10286
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle AI-Assisted Geometric Analysis of Cultured Neuronal Networks: Parallels with the Cosmic Web
Kurz, Wolfgang
Baranes, Danny
Neurons and Cognition
Building on evidence of structural parallels between brain networks and the cosmic web [1], we apply AI-based geometric analysis to cultured neuronal networks. Isolated neurons self-organize into dendritic lattices shaped by reproducible wiring rules. These lattices show non-random features-frequent dendritic convergence, hub nodes, small-world connectivity, and large voids. Synaptic contacts cluster and strengthen at hubs. Strikingly, these properties mirror the cosmic web: dendritic branches resemble cosmic filaments and synapses map to galaxies. Quantitative metrics align across systems, suggesting shared underlying geometric principles. We invite cross-disciplinary collaboration to interrogate and extend these parallels.
title AI-Assisted Geometric Analysis of Cultured Neuronal Networks: Parallels with the Cosmic Web
topic Neurons and Cognition
url https://arxiv.org/abs/2510.10286