MedCoAct: Confidence-Aware Multi-Agent Collaboration for Complete Clinical Decision

Fuente: arXiv
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Autori principali: Zheng, Hongjie, Shi, Zesheng, Yi, Ping
Natura: Preprint
Pubblicazione: 2025
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author Zheng, Hongjie
Shi, Zesheng
Yi, Ping
author_facet Zheng, Hongjie
Shi, Zesheng
Yi, Ping
contents Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic reasoning and medication decisions. We identify a core limitation: existing medical AI systems process tasks in isolation without the cross-validation and knowledge integration found in clinical teams, reducing their effectiveness in real-world healthcare scenarios. To transform the isolation paradigm into a collaborative approach, we propose MedCoAct, a confidence-aware multi-agent framework that simulates clinical collaboration by integrating specialized doctor and pharmacist agents, and present a benchmark, DrugCareQA, to evaluate medical AI capabilities in integrated diagnosis and treatment workflows. Our results demonstrate that MedCoAct achieves 67.58\% diagnostic accuracy and 67.58\% medication recommendation accuracy, outperforming single agent framework by 7.04\% and 7.08\% respectively. This collaborative approach generalizes well across diverse medical domains, proving especially effective for telemedicine consultations and routine clinical scenarios, while providing interpretable decision-making pathways.
format Preprint
id arxiv_https___arxiv_org_abs_2510_10461
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MedCoAct: Confidence-Aware Multi-Agent Collaboration for Complete Clinical Decision
Zheng, Hongjie
Shi, Zesheng
Yi, Ping
Artificial Intelligence
Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic reasoning and medication decisions. We identify a core limitation: existing medical AI systems process tasks in isolation without the cross-validation and knowledge integration found in clinical teams, reducing their effectiveness in real-world healthcare scenarios. To transform the isolation paradigm into a collaborative approach, we propose MedCoAct, a confidence-aware multi-agent framework that simulates clinical collaboration by integrating specialized doctor and pharmacist agents, and present a benchmark, DrugCareQA, to evaluate medical AI capabilities in integrated diagnosis and treatment workflows. Our results demonstrate that MedCoAct achieves 67.58\% diagnostic accuracy and 67.58\% medication recommendation accuracy, outperforming single agent framework by 7.04\% and 7.08\% respectively. This collaborative approach generalizes well across diverse medical domains, proving especially effective for telemedicine consultations and routine clinical scenarios, while providing interpretable decision-making pathways.
title MedCoAct: Confidence-Aware Multi-Agent Collaboration for Complete Clinical Decision
topic Artificial Intelligence
url https://arxiv.org/abs/2510.10461