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Main Authors: Zhong, Chen, Yang, Yuxuan, Zhang, Xinyue, Ma, Ruohan, Guo, Yong, Li, Gang, Li, Jupeng
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2510.10462
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author Zhong, Chen
Yang, Yuxuan
Zhang, Xinyue
Ma, Ruohan
Guo, Yong
Li, Gang
Li, Jupeng
author_facet Zhong, Chen
Yang, Yuxuan
Zhang, Xinyue
Ma, Ruohan
Guo, Yong
Li, Gang
Li, Jupeng
contents Medical image segmentation annotation suffers from inter-rater variability (IRV) due to differences in annotators' expertise and the inherent blurriness of medical images. Standard approaches that simply average expert labels are flawed, as they discard the valuable clinical uncertainty revealed in disagreements. We introduce a fundamentally new approach with our group decision simulation framework, which works by mimicking the collaborative decision-making process of a clinical panel. Under this framework, an Expert Signature Generator (ESG) learns to represent individual annotator styles in a unique latent space. A Simulated Consultation Module (SCM) then intelligently generates the final segmentation by sampling from this space. This method achieved state-of-the-art results on challenging CBCT and MRI datasets (92.11% and 90.72% Dice scores). By treating expert disagreement as a useful signal instead of noise, our work provides a clear path toward more robust and trustworthy AI systems for healthcare.
format Preprint
id arxiv_https___arxiv_org_abs_2510_10462
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Learning from Disagreement: A Group Decision Simulation Framework for Robust Medical Image Segmentation
Zhong, Chen
Yang, Yuxuan
Zhang, Xinyue
Ma, Ruohan
Guo, Yong
Li, Gang
Li, Jupeng
Computer Vision and Pattern Recognition
Artificial Intelligence
Medical image segmentation annotation suffers from inter-rater variability (IRV) due to differences in annotators' expertise and the inherent blurriness of medical images. Standard approaches that simply average expert labels are flawed, as they discard the valuable clinical uncertainty revealed in disagreements. We introduce a fundamentally new approach with our group decision simulation framework, which works by mimicking the collaborative decision-making process of a clinical panel. Under this framework, an Expert Signature Generator (ESG) learns to represent individual annotator styles in a unique latent space. A Simulated Consultation Module (SCM) then intelligently generates the final segmentation by sampling from this space. This method achieved state-of-the-art results on challenging CBCT and MRI datasets (92.11% and 90.72% Dice scores). By treating expert disagreement as a useful signal instead of noise, our work provides a clear path toward more robust and trustworthy AI systems for healthcare.
title Learning from Disagreement: A Group Decision Simulation Framework for Robust Medical Image Segmentation
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2510.10462