Shallow Robustness, Deep Vulnerabilities: Multi-Turn Evaluation of Medical LLMs

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Main Authors: Manczak, Blazej, Lin, Eric, Eiras, Francisco, Neill, James O', Mugunthan, Vaikkunth
Format: Preprint
Published: 2025
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author Manczak, Blazej
Lin, Eric
Eiras, Francisco
Neill, James O'
Mugunthan, Vaikkunth
author_facet Manczak, Blazej
Lin, Eric
Eiras, Francisco
Neill, James O'
Mugunthan, Vaikkunth
contents Large language models (LLMs) are rapidly transitioning into medical clinical use, yet their reliability under realistic, multi-turn interactions remains poorly understood. Existing evaluation frameworks typically assess single-turn question answering under idealized conditions, overlooking the complexities of medical consultations where conflicting input, misleading context, and authority influence are common. We introduce MedQA-Followup, a framework for systematically evaluating multi-turn robustness in medical question answering. Our approach distinguishes between shallow robustness (resisting misleading initial context) and deep robustness (maintaining accuracy when answers are challenged across turns), while also introducing an indirect-direct axis that separates contextual framing (indirect) from explicit suggestion (direct). Using controlled interventions on the MedQA dataset, we evaluate five state-of-the-art LLMs and find that while models perform reasonably well under shallow perturbations, they exhibit severe vulnerabilities in multi-turn settings, with accuracy dropping from 91.2% to as low as 13.5% for Claude Sonnet 4. Counterintuitively, indirect, context-based interventions are often more harmful than direct suggestions, yielding larger accuracy drops across models and exposing a significant vulnerability for clinical deployment. Further compounding analyses reveal model differences, with some showing additional performance drops under repeated interventions while others partially recovering or even improving. These findings highlight multi-turn robustness as a critical but underexplored dimension for safe and reliable deployment of medical LLMs.
format Preprint
id arxiv_https___arxiv_org_abs_2510_12255
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Shallow Robustness, Deep Vulnerabilities: Multi-Turn Evaluation of Medical LLMs
Manczak, Blazej
Lin, Eric
Eiras, Francisco
Neill, James O'
Mugunthan, Vaikkunth
Computation and Language
Artificial Intelligence
I.2.7; I.2.6; J.3
Large language models (LLMs) are rapidly transitioning into medical clinical use, yet their reliability under realistic, multi-turn interactions remains poorly understood. Existing evaluation frameworks typically assess single-turn question answering under idealized conditions, overlooking the complexities of medical consultations where conflicting input, misleading context, and authority influence are common. We introduce MedQA-Followup, a framework for systematically evaluating multi-turn robustness in medical question answering. Our approach distinguishes between shallow robustness (resisting misleading initial context) and deep robustness (maintaining accuracy when answers are challenged across turns), while also introducing an indirect-direct axis that separates contextual framing (indirect) from explicit suggestion (direct). Using controlled interventions on the MedQA dataset, we evaluate five state-of-the-art LLMs and find that while models perform reasonably well under shallow perturbations, they exhibit severe vulnerabilities in multi-turn settings, with accuracy dropping from 91.2% to as low as 13.5% for Claude Sonnet 4. Counterintuitively, indirect, context-based interventions are often more harmful than direct suggestions, yielding larger accuracy drops across models and exposing a significant vulnerability for clinical deployment. Further compounding analyses reveal model differences, with some showing additional performance drops under repeated interventions while others partially recovering or even improving. These findings highlight multi-turn robustness as a critical but underexplored dimension for safe and reliable deployment of medical LLMs.
title Shallow Robustness, Deep Vulnerabilities: Multi-Turn Evaluation of Medical LLMs
topic Computation and Language
Artificial Intelligence
I.2.7; I.2.6; J.3
url https://arxiv.org/abs/2510.12255