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Main Authors: Zeng, Minlin, Zhou, Zhipeng, Qiu, Yang, McKeown, Martin J., Shen, Zhiqi
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2510.15748
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author Zeng, Minlin
Zhou, Zhipeng
Qiu, Yang
McKeown, Martin J.
Shen, Zhiqi
author_facet Zeng, Minlin
Zhou, Zhipeng
Qiu, Yang
McKeown, Martin J.
Shen, Zhiqi
contents Parkinson's disease assessment has garnered growing interest in recent years, particularly with the advent of sensor data and machine learning techniques. Among these, multimodal approaches have demonstrated strong performance by effectively integrating complementary information from various data sources. However, two major limitations hinder their practical application: (1) the need to synchronize all modalities during training, and (2) the dependence on all modalities during inference. To address these issues, we propose the first Parkinson's assessment system that formulates multimodal learning as a multi-objective optimization (MOO) problem. This not only allows for more flexible modality requirements during both training and inference, but also handles modality collapse issue during multimodal information fusion. In addition, to mitigate the imbalance within individual modalities, we introduce a margin-based class rebalancing strategy to enhance category learning. We conduct extensive experiments on three public datasets under both synchronous and asynchronous settings. The results show that our framework-Towards Relaxed InPuts (TRIP)-achieves state-of-the-art performance, outperforming the best baselines by 16.48, 6.89, and 11.55 percentage points in the asynchronous setting, and by 4.86 and 2.30 percentage points in the synchronous setting, highlighting its effectiveness and adaptability.
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publishDate 2025
record_format arxiv
spellingShingle Towards Relaxed Multimodal Inputs for Gait-based Parkinson's Disease Assessment
Zeng, Minlin
Zhou, Zhipeng
Qiu, Yang
McKeown, Martin J.
Shen, Zhiqi
Artificial Intelligence
Parkinson's disease assessment has garnered growing interest in recent years, particularly with the advent of sensor data and machine learning techniques. Among these, multimodal approaches have demonstrated strong performance by effectively integrating complementary information from various data sources. However, two major limitations hinder their practical application: (1) the need to synchronize all modalities during training, and (2) the dependence on all modalities during inference. To address these issues, we propose the first Parkinson's assessment system that formulates multimodal learning as a multi-objective optimization (MOO) problem. This not only allows for more flexible modality requirements during both training and inference, but also handles modality collapse issue during multimodal information fusion. In addition, to mitigate the imbalance within individual modalities, we introduce a margin-based class rebalancing strategy to enhance category learning. We conduct extensive experiments on three public datasets under both synchronous and asynchronous settings. The results show that our framework-Towards Relaxed InPuts (TRIP)-achieves state-of-the-art performance, outperforming the best baselines by 16.48, 6.89, and 11.55 percentage points in the asynchronous setting, and by 4.86 and 2.30 percentage points in the synchronous setting, highlighting its effectiveness and adaptability.
title Towards Relaxed Multimodal Inputs for Gait-based Parkinson's Disease Assessment
topic Artificial Intelligence
url https://arxiv.org/abs/2510.15748