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Main Authors: Gibford, Shawn M., Boskabadi, Mohammad Reza, Savoie, Christopher J., Mansouri, Seyed Soheil
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2510.17688
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author Gibford, Shawn M.
Boskabadi, Mohammad Reza
Savoie, Christopher J.
Mansouri, Seyed Soheil
author_facet Gibford, Shawn M.
Boskabadi, Mohammad Reza
Savoie, Christopher J.
Mansouri, Seyed Soheil
contents Data scarcity and sparsity in bio-manufacturing poses challenges for accurate model development, process monitoring, and optimization. We aim to replicate and capture the complex dynamics of industrial bioprocesses by proposing the use of a Quantum Wasserstein Generative Adversarial Network with Gradient Penalty (QWGAN-GP) to generate synthetic time series data for industrially relevant processes. The generator within our GAN is comprised of a Parameterized Quantum Circuit (PQC). This methodology offers potential advantages in process monitoring, modeling, forecasting, and optimization, enabling more efficient bioprocess management by reducing the dependence on scarce experimental data. Our results demonstrate acceptable performance in capturing the temporal dynamics of real bioprocess data. We focus on Optical Density, a key measurement for Dry Biomass estimation. The data generated showed high fidelity to the actual historical experimental data. This intersection of quantum computing and machine learning has opened new frontiers in data analysis and generation, particularly in computationally intensive fields, for use cases such as increasing prediction accuracy for soft sensor design or for use in predictive control.
format Preprint
id arxiv_https___arxiv_org_abs_2510_17688
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Quantum Synthetic Data Generation for Industrial Bioprocess Monitoring
Gibford, Shawn M.
Boskabadi, Mohammad Reza
Savoie, Christopher J.
Mansouri, Seyed Soheil
Emerging Technologies
Machine Learning
Data scarcity and sparsity in bio-manufacturing poses challenges for accurate model development, process monitoring, and optimization. We aim to replicate and capture the complex dynamics of industrial bioprocesses by proposing the use of a Quantum Wasserstein Generative Adversarial Network with Gradient Penalty (QWGAN-GP) to generate synthetic time series data for industrially relevant processes. The generator within our GAN is comprised of a Parameterized Quantum Circuit (PQC). This methodology offers potential advantages in process monitoring, modeling, forecasting, and optimization, enabling more efficient bioprocess management by reducing the dependence on scarce experimental data. Our results demonstrate acceptable performance in capturing the temporal dynamics of real bioprocess data. We focus on Optical Density, a key measurement for Dry Biomass estimation. The data generated showed high fidelity to the actual historical experimental data. This intersection of quantum computing and machine learning has opened new frontiers in data analysis and generation, particularly in computationally intensive fields, for use cases such as increasing prediction accuracy for soft sensor design or for use in predictive control.
title Quantum Synthetic Data Generation for Industrial Bioprocess Monitoring
topic Emerging Technologies
Machine Learning
url https://arxiv.org/abs/2510.17688