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Main Authors: Albani, Mhd Adnan, Sonbol, Riad
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2510.17703
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author Albani, Mhd Adnan
Sonbol, Riad
author_facet Albani, Mhd Adnan
Sonbol, Riad
contents Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support early detection of Parkinson's disease based on hand-drawn images; however, we identified two major limitations in the related works: (1) the lack of sufficient datasets, (2) the robustness when dealing with unseen patient data. In this paper, we propose a new approach to detect Parkinson's disease that consists of two stages: The first stage classifies based on their drawing type(circle, meander, spiral), and the second stage extracts the required features from the images and detects Parkinson's disease. We overcame the previous two limitations by applying a chunking strategy where we divide each image into 2x2 chunks. Each chunk is processed separately when extracting features and recognizing Parkinson's disease indicators. To make the final classification, an ensemble method is used to merge the decisions made from each chunk. Our evaluation shows that our proposed approach outperforms the top performing state-of-the-art approaches, in particular on unseen patients. On the NewHandPD dataset our approach, it achieved 97.08% accuracy for seen patients and 94.91% for unseen patients, our proposed approach maintained a gap of only 2.17 percentage points, compared to the 4.76-point drop observed in prior work.
format Preprint
id arxiv_https___arxiv_org_abs_2510_17703
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Cross-Patient Generalization in AI-Based Parkinson s Disease Detection
Albani, Mhd Adnan
Sonbol, Riad
Computer Vision and Pattern Recognition
Artificial Intelligence
Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support early detection of Parkinson's disease based on hand-drawn images; however, we identified two major limitations in the related works: (1) the lack of sufficient datasets, (2) the robustness when dealing with unseen patient data. In this paper, we propose a new approach to detect Parkinson's disease that consists of two stages: The first stage classifies based on their drawing type(circle, meander, spiral), and the second stage extracts the required features from the images and detects Parkinson's disease. We overcame the previous two limitations by applying a chunking strategy where we divide each image into 2x2 chunks. Each chunk is processed separately when extracting features and recognizing Parkinson's disease indicators. To make the final classification, an ensemble method is used to merge the decisions made from each chunk. Our evaluation shows that our proposed approach outperforms the top performing state-of-the-art approaches, in particular on unseen patients. On the NewHandPD dataset our approach, it achieved 97.08% accuracy for seen patients and 94.91% for unseen patients, our proposed approach maintained a gap of only 2.17 percentage points, compared to the 4.76-point drop observed in prior work.
title Enhancing Cross-Patient Generalization in AI-Based Parkinson s Disease Detection
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2510.17703