LAND: Lung and Nodule Diffusion for 3D Chest CT Synthesis with Anatomical Guidance
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arXiv
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| Format: | Preprint |
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2025
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| _version_ | 1866911223758454784 |
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| author | Oliveras, Anna Marí, Roger Redondo, Rafael Guardià, Oriol Tost, Ana Nagarajan, Bhalaji Migliorelli, Carolina Ribas, Vicent Radeva, Petia |
| author_facet | Oliveras, Anna Marí, Roger Redondo, Rafael Guardià, Oriol Tost, Ana Nagarajan, Bhalaji Migliorelli, Carolina Ribas, Vicent Radeva, Petia |
| contents | This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single mid-range GPU, significantly lowering the computational cost compared to existing approaches. The conditioning masks delineate lung and nodule regions, enabling precise control over the output anatomical features. Experimental results demonstrate that conditioning solely on nodule masks leads to anatomically incorrect outputs, highlighting the importance of incorporating global lung structure for accurate conditional synthesis. The proposed approach supports the generation of diverse CT volumes with and without lung nodules of varying attributes, providing a valuable tool for training AI models or healthcare professionals. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2510_18446 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | LAND: Lung and Nodule Diffusion for 3D Chest CT Synthesis with Anatomical Guidance Oliveras, Anna Marí, Roger Redondo, Rafael Guardià, Oriol Tost, Ana Nagarajan, Bhalaji Migliorelli, Carolina Ribas, Vicent Radeva, Petia Computer Vision and Pattern Recognition This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single mid-range GPU, significantly lowering the computational cost compared to existing approaches. The conditioning masks delineate lung and nodule regions, enabling precise control over the output anatomical features. Experimental results demonstrate that conditioning solely on nodule masks leads to anatomically incorrect outputs, highlighting the importance of incorporating global lung structure for accurate conditional synthesis. The proposed approach supports the generation of diverse CT volumes with and without lung nodules of varying attributes, providing a valuable tool for training AI models or healthcare professionals. |
| title | LAND: Lung and Nodule Diffusion for 3D Chest CT Synthesis with Anatomical Guidance |
| topic | Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2510.18446 |