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Main Authors: Park, Juhyung, Hong, Rokgi, Yoo, Roh-Eul, Koo, Jaehyeon, Chun, Se Young, Choi, Seung Hong, Lee, Jongho
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2510.19472
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author Park, Juhyung
Hong, Rokgi
Yoo, Roh-Eul
Koo, Jaehyeon
Chun, Se Young
Choi, Seung Hong
Lee, Jongho
author_facet Park, Juhyung
Hong, Rokgi
Yoo, Roh-Eul
Koo, Jaehyeon
Chun, Se Young
Choi, Seung Hong
Lee, Jongho
contents Recent advancements in artificial intelligence have created transformative capabilities in image synthesis and generation, enabling diverse research fields to innovate at revolutionary speed and spectrum. In this study, we leverage this generative power to introduce a new paradigm for accelerating Magnetic Resonance Imaging (MRI), introducing a shift from image reconstruction to proactive predictive imaging. Despite being a cornerstone of modern patient care, MRI's lengthy acquisition times limit clinical throughput. Our novel framework addresses this challenge by first predicting a target contrast image, which then serves as a data-driven prior for reconstructing highly under-sampled data. This informative prior is predicted by a generative model conditioned on diverse data sources, such as other contrast images, previously scanned images, acquisition parameters, patient information. We demonstrate this approach with two key applications: (1) reconstructing FLAIR images using predictions from T1w and/or T2w scans, and (2) reconstructing T1w images using predictions from previously acquired T1w scans. The framework was evaluated on internal and multiple public datasets (total 14,921 scans; 1,051,904 slices), including multi-channel k-space data, for a range of high acceleration factors (x4, x8 and x12). The results demonstrate that our prediction-prior reconstruction method significantly outperforms other approaches, including those with alternative or no prior information. Through this framework we introduce a fundamental shift from image reconstruction towards a new paradigm of predictive imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2510_19472
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Predicting before Reconstruction: A generative prior framework for MRI acceleration
Park, Juhyung
Hong, Rokgi
Yoo, Roh-Eul
Koo, Jaehyeon
Chun, Se Young
Choi, Seung Hong
Lee, Jongho
Computer Vision and Pattern Recognition
Recent advancements in artificial intelligence have created transformative capabilities in image synthesis and generation, enabling diverse research fields to innovate at revolutionary speed and spectrum. In this study, we leverage this generative power to introduce a new paradigm for accelerating Magnetic Resonance Imaging (MRI), introducing a shift from image reconstruction to proactive predictive imaging. Despite being a cornerstone of modern patient care, MRI's lengthy acquisition times limit clinical throughput. Our novel framework addresses this challenge by first predicting a target contrast image, which then serves as a data-driven prior for reconstructing highly under-sampled data. This informative prior is predicted by a generative model conditioned on diverse data sources, such as other contrast images, previously scanned images, acquisition parameters, patient information. We demonstrate this approach with two key applications: (1) reconstructing FLAIR images using predictions from T1w and/or T2w scans, and (2) reconstructing T1w images using predictions from previously acquired T1w scans. The framework was evaluated on internal and multiple public datasets (total 14,921 scans; 1,051,904 slices), including multi-channel k-space data, for a range of high acceleration factors (x4, x8 and x12). The results demonstrate that our prediction-prior reconstruction method significantly outperforms other approaches, including those with alternative or no prior information. Through this framework we introduce a fundamental shift from image reconstruction towards a new paradigm of predictive imaging.
title Predicting before Reconstruction: A generative prior framework for MRI acceleration
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2510.19472