Automated HIV Screening on Dutch Electronic Health Records with Large Language Models

Fuente: arXiv
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Auteurs principaux: Zhou, Lang, Jhingoer, Amrish, Luo, Yinghao, Vliegenthart--Jongbloed, Klaske, Jordans, Carlijn, Werkhoven, Ben, Seinen, Tom, van Mulligen, Erik, Rokx, Casper, Li, Yunlei
Format: Preprint
Publié: 2025
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author Zhou, Lang
Jhingoer, Amrish
Luo, Yinghao
Vliegenthart--Jongbloed, Klaske
Jordans, Carlijn
Werkhoven, Ben
Seinen, Tom
van Mulligen, Erik
Rokx, Casper
Li, Yunlei
author_facet Zhou, Lang
Jhingoer, Amrish
Luo, Yinghao
Vliegenthart--Jongbloed, Klaske
Jordans, Carlijn
Werkhoven, Ben
Seinen, Tom
van Mulligen, Erik
Rokx, Casper
Li, Yunlei
contents Efficient screening and early diagnosis of HIV are critical for reducing onward transmission. Although large scale laboratory testing is not feasible, the widespread adoption of Electronic Health Records (EHRs) offers new opportunities to address this challenge. Existing research primarily focuses on applying machine learning methods to structured data, such as patient demographics, for improving HIV diagnosis. However, these approaches often overlook unstructured text data such as clinical notes, which potentially contain valuable information relevant to HIV risk. In this study, we propose a novel pipeline that leverages a Large Language Model (LLM) to analyze unstructured EHR text and determine a patient's eligibility for further HIV testing. Experimental results on clinical data from Erasmus University Medical Center Rotterdam demonstrate that our pipeline achieved high accuracy while maintaining a low false negative rate.
format Preprint
id arxiv_https___arxiv_org_abs_2510_19879
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Automated HIV Screening on Dutch Electronic Health Records with Large Language Models
Zhou, Lang
Jhingoer, Amrish
Luo, Yinghao
Vliegenthart--Jongbloed, Klaske
Jordans, Carlijn
Werkhoven, Ben
Seinen, Tom
van Mulligen, Erik
Rokx, Casper
Li, Yunlei
Computation and Language
Efficient screening and early diagnosis of HIV are critical for reducing onward transmission. Although large scale laboratory testing is not feasible, the widespread adoption of Electronic Health Records (EHRs) offers new opportunities to address this challenge. Existing research primarily focuses on applying machine learning methods to structured data, such as patient demographics, for improving HIV diagnosis. However, these approaches often overlook unstructured text data such as clinical notes, which potentially contain valuable information relevant to HIV risk. In this study, we propose a novel pipeline that leverages a Large Language Model (LLM) to analyze unstructured EHR text and determine a patient's eligibility for further HIV testing. Experimental results on clinical data from Erasmus University Medical Center Rotterdam demonstrate that our pipeline achieved high accuracy while maintaining a low false negative rate.
title Automated HIV Screening on Dutch Electronic Health Records with Large Language Models
topic Computation and Language
url https://arxiv.org/abs/2510.19879