Beyond MedQA: Towards Real-world Clinical Decision Making in the Era of LLMs

Fuente: arXiv
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Autori principali: Xiao, Yunpeng, Yang, Carl, Mai, Mark, Hu, Xiao, Shu, Kai
Natura: Preprint
Pubblicazione: 2025
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author Xiao, Yunpeng
Yang, Carl
Mai, Mark
Hu, Xiao
Shu, Kai
author_facet Xiao, Yunpeng
Yang, Carl
Mai, Mark
Hu, Xiao
Shu, Kai
contents Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world clinical decision-making. Based on this, we propose a unifying paradigm that characterizes clinical decision-making tasks along two dimensions: Clinical Backgrounds and Clinical Questions. As the background and questions approach the real clinical environment, the difficulty increases. We summarize the settings of existing datasets and benchmarks along two dimensions. Then we review methods to address clinical decision-making, including training-time and test-time techniques, and summarize when they help. Next, we extend evaluation beyond accuracy to include efficiency, explainability. Finally, we highlight open challenges. Our paradigm clarifies assumptions, standardizes comparisons, and guides the development of clinically meaningful LLMs.
format Preprint
id arxiv_https___arxiv_org_abs_2510_20001
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Beyond MedQA: Towards Real-world Clinical Decision Making in the Era of LLMs
Xiao, Yunpeng
Yang, Carl
Mai, Mark
Hu, Xiao
Shu, Kai
Computation and Language
Artificial Intelligence
Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world clinical decision-making. Based on this, we propose a unifying paradigm that characterizes clinical decision-making tasks along two dimensions: Clinical Backgrounds and Clinical Questions. As the background and questions approach the real clinical environment, the difficulty increases. We summarize the settings of existing datasets and benchmarks along two dimensions. Then we review methods to address clinical decision-making, including training-time and test-time techniques, and summarize when they help. Next, we extend evaluation beyond accuracy to include efficiency, explainability. Finally, we highlight open challenges. Our paradigm clarifies assumptions, standardizes comparisons, and guides the development of clinically meaningful LLMs.
title Beyond MedQA: Towards Real-world Clinical Decision Making in the Era of LLMs
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2510.20001