To MCMC or not to MCMC: Evaluating non-MCMC methods for Bayesian penalized regression

Fuente: arXiv
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Autori principali: van Leeuwen, Florian D., van Erp, Sara
Natura: Preprint
Pubblicazione: 2025
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author van Leeuwen, Florian D.
van Erp, Sara
author_facet van Leeuwen, Florian D.
van Erp, Sara
contents Markov Chain Monte Carlo (MCMC) sampling is computationally expensive, especially for complex models. Alternative methods make simplifying assumptions about the posterior to reduce computational burden, but their impact on predictive performance remains unclear. This paper compares MCMC and non-MCMC methods for high-dimensional penalized regression, examining when computational shortcuts are justified for prediction tasks. We conduct a comprehensive simulation study using high-dimensional tabular data, then validate findings with empirical datasets featuring both continuous and binary outcomes. An in-depth analysis of one dataset provides a step-by-step tutorial implementing various algorithms in R. Our results show that mean-field variational inference consistently performs comparably to MCMC methods. In simulations, mean-field VI exhibited 3-90\% higher MSE across scenarios while reducing runtime by 7-30x compared to Hamiltonian Monte Carlo. Empirical datasets revealed dramatic speed-ups (100-400x) in some cases with similar or superior predictive performance. However, performance varied: some cases showed over 100x MSE increases with only 30x speed-ups, highlighting the context-dependent nature of these trade-offs.
format Preprint
id arxiv_https___arxiv_org_abs_2510_20947
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle To MCMC or not to MCMC: Evaluating non-MCMC methods for Bayesian penalized regression
van Leeuwen, Florian D.
van Erp, Sara
Computation
Methodology
Markov Chain Monte Carlo (MCMC) sampling is computationally expensive, especially for complex models. Alternative methods make simplifying assumptions about the posterior to reduce computational burden, but their impact on predictive performance remains unclear. This paper compares MCMC and non-MCMC methods for high-dimensional penalized regression, examining when computational shortcuts are justified for prediction tasks. We conduct a comprehensive simulation study using high-dimensional tabular data, then validate findings with empirical datasets featuring both continuous and binary outcomes. An in-depth analysis of one dataset provides a step-by-step tutorial implementing various algorithms in R. Our results show that mean-field variational inference consistently performs comparably to MCMC methods. In simulations, mean-field VI exhibited 3-90\% higher MSE across scenarios while reducing runtime by 7-30x compared to Hamiltonian Monte Carlo. Empirical datasets revealed dramatic speed-ups (100-400x) in some cases with similar or superior predictive performance. However, performance varied: some cases showed over 100x MSE increases with only 30x speed-ups, highlighting the context-dependent nature of these trade-offs.
title To MCMC or not to MCMC: Evaluating non-MCMC methods for Bayesian penalized regression
topic Computation
Methodology
url https://arxiv.org/abs/2510.20947