AdvBlur: Adversarial Blur for Robust Diabetic Retinopathy Classification and Cross-Domain Generalization

Fuente: arXiv
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Autori principali: Kanagalingam, Heethanjan, Pathmanathan, Thenukan, Vathanakumar, Mokeeshan, Mukunthan, Tharmakulasingam
Natura: Preprint
Pubblicazione: 2025
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author Kanagalingam, Heethanjan
Pathmanathan, Thenukan
Vathanakumar, Mokeeshan
Mukunthan, Tharmakulasingam
author_facet Kanagalingam, Heethanjan
Pathmanathan, Thenukan
Vathanakumar, Mokeeshan
Mukunthan, Tharmakulasingam
contents Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, yet early and accurate detection can significantly improve treatment outcomes. While numerous Deep learning (DL) models have been developed to predict DR from fundus images, many face challenges in maintaining robustness due to distributional variations caused by differences in acquisition devices, demographic disparities, and imaging conditions. This paper addresses this critical limitation by proposing a novel DR classification approach, a method called AdvBlur. Our method integrates adversarial blurred images into the dataset and employs a dual-loss function framework to address domain generalization. This approach effectively mitigates the impact of unseen distributional variations, as evidenced by comprehensive evaluations across multiple datasets. Additionally, we conduct extensive experiments to explore the effects of factors such as camera type, low-quality images, and dataset size. Furthermore, we perform ablation studies on blurred images and the loss function to ensure the validity of our choices. The experimental results demonstrate the effectiveness of our proposed method, achieving competitive performance compared to state-of-the-art domain generalization DR models on unseen external datasets.
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id arxiv_https___arxiv_org_abs_2510_24000
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle AdvBlur: Adversarial Blur for Robust Diabetic Retinopathy Classification and Cross-Domain Generalization
Kanagalingam, Heethanjan
Pathmanathan, Thenukan
Vathanakumar, Mokeeshan
Mukunthan, Tharmakulasingam
Computer Vision and Pattern Recognition
Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, yet early and accurate detection can significantly improve treatment outcomes. While numerous Deep learning (DL) models have been developed to predict DR from fundus images, many face challenges in maintaining robustness due to distributional variations caused by differences in acquisition devices, demographic disparities, and imaging conditions. This paper addresses this critical limitation by proposing a novel DR classification approach, a method called AdvBlur. Our method integrates adversarial blurred images into the dataset and employs a dual-loss function framework to address domain generalization. This approach effectively mitigates the impact of unseen distributional variations, as evidenced by comprehensive evaluations across multiple datasets. Additionally, we conduct extensive experiments to explore the effects of factors such as camera type, low-quality images, and dataset size. Furthermore, we perform ablation studies on blurred images and the loss function to ensure the validity of our choices. The experimental results demonstrate the effectiveness of our proposed method, achieving competitive performance compared to state-of-the-art domain generalization DR models on unseen external datasets.
title AdvBlur: Adversarial Blur for Robust Diabetic Retinopathy Classification and Cross-Domain Generalization
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2510.24000